Stem-loop sequence dme-mir-124

AccessionMI0000373 (change log)
DescriptionDrosophila melanogaster miR-124 stem-loop
Gene family MIPF0000021; mir-124
Literature search

19 open access papers mention dme-mir-124
(337 sentences)

   ---ucauuuggua     uu   c      c      ag    a    uau 
5'              cguuu  cuc ugguau cacugu  gccu uaug   u
                |||||  ||| |||||| ||||||  |||| ||||   u
3'              gcaag  gag accgua guggcg  cgga auac   c
   uaaacaucuugac     -c   a      a      ca    -    cac 
Get sequence
Deep sequencing
373967 reads, 2.19e+04 reads per million, 48 experiments
Confidence Annotation confidence: high
Feedback: Do you believe this miRNA is real?

miR-124 was reported independently in references [1] and [2]. Computational prediction followed by northern blotting confirmed that the strand containing the predicted miR is predominantly expressed [1]. Reference [2] confirmed the 5' end of the excised miRNA by cloning and reported a length distribution of 19-23 nt with 23 nt the most commonly expressed.

Genome context
Coordinates (Release_6; GCA_000001215.4) Overlapping transcripts
chr2L: 17566370-17566469 [+]
Clustered miRNAs
< 10kb from dme-mir-124
dme-mir-124chr2L: 17566370-17566469 [+]
dme-mir-287chr2L: 17574610-17574702 [+]
Database links

Mature sequence dme-miR-124-5p

Accession MIMAT0020813

23 - 


 - 45

Get sequence
Deep sequencing8514 reads, 42 experiments
Evidence not experimental
Database links

Mature sequence dme-miR-124-3p

Accession MIMAT0000351
Previous IDsdme-miR-124

57 - 


 - 79

Get sequence
Deep sequencing365453 reads, 48 experiments
Evidence experimental; cloned [2], Northern [2-3], 454 [4-5], Illumina [5]
Database links
Predicted targets


PMID:12844358 "Computational identification of Drosophila microRNA genes" Lai EC, Tomancak P, Williams RW, Rubin GM Genome Biol. 4:R42(2003).
PMID:12919683 "The small RNA profile during Drosophila melanogaster development" Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T Dev Cell. 5:337-350(2003).
PMID:17989254 "Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs" Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC Genome Res. 17:1850-1864(2007).
PMID:17989255 "Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes" Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis M Genome Res. 17:1865-1879(2007).