Stem-loop sequence hsa-mir-30b

Accession

MI0000441 (change log)

Symbol

HGNC:MIR30B

Description

Homo sapiens miR-30b stem-loop

Gene family

MIPF0000005; mir-30

Literature search

398 open access papers mention hsa-mir-30b
(1757 sentences)

Stem-loop

   a     uu      cau          u  -a        uaaua 
5'  ccaag  ucaguu   guaaacaucc ac  cucagcug     c
    |||||  ||||||   |||||||||| ||  ||||||||      
3'  gguuc  agucga   cauuuguagg ug  gggucggu     a
   a     --      cuu          -  ga        uaggu 

Deep sequencing

1118545 reads, 2.25e+03 reads per million, 159 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

This miRNA sequence is predicted based on homology to a verified miRNA from mouse [1], later verified in human [2].

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr8: 134800520-134800607 [-]
• Overlapping transcripts:

  antisense

  OTTHUMT00000379148 ; CTD-2588J1.1-001; intron 1

  ENST00000517695 ; CTD-2588J1.1-001; intron 1

Clustered miRNAs

< 10kb from hsa-mir-30b

• hsa-mir-30d: chr8: 134804876-134804945 [-]
• hsa-mir-30b: chr8: 134800520-134800607 [-]

Database links

• EntrezGene:MIR30B
• HGNC:MIR30B
• RNAcentral:URS00003426E6_9606
• miRBase Tracker:MI0000441

Mature sequence hsa-miR-30b-5p

• Accession: MIMAT0000420
• Previous IDs: hsa-miR-30b
• Sequence: 17 - uguaaacauccuacacucagcu - 38
• Deep sequencing: 1110974 reads, 159 experiments
• Evidence: experimental; cloned [2-3]
• Database links:
  • RNAcentral:URS00005165DA_9606
• Predicted targets:
  • TargetMiner:hsa-miR-30b-5p
  • TargetScanVert:hsa-miR-30b-5p
  • miRDB:hsa-miR-30b-5p
  • microrna.org:hsa-miR-30b-5p

Mature sequence hsa-miR-30b-3p

• Accession: MIMAT0004589
• Previous IDs: hsa-miR-30b*
• Sequence: 55 - cugggagguggauguuuacuuc - 76
• Deep sequencing: 7535 reads, 155 experiments
• Evidence: experimental; cloned [2]
• Database links:
  • RNAcentral:URS00002152A8_9606
• Predicted targets:
  • TargetMiner:hsa-miR-30b-3p
  • TargetScanVert:hsa-miR-30b-3p
  • miRDB:hsa-miR-30b-3p
  • microrna.org:hsa-miR-30b-3p

References

1. PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:17616659 "Patterns of known and novel small RNAs in human cervical cancer" Lui WO, Pourmand N, Patterson BK, Fire A Cancer Res. 67:6031-6043(2007).