Stem-loop mmu-mir-212

Accession

MI0000696

Symbol

MGI: Mir212

Description

Mus musculus mmu-mir-212 precursor miRNA

Gene family

MIPF0000065; mir-132

Literature search

76 open access papers mention mmu-mir-212
(633 sentences)

Sequence

23017 reads, 178 reads per million, 102 experiments

gggcagcgcgccggcACCUUGGCUCUAGACUGCUUACUgcccgggccgccuucagUAACAGUCUCCAGUCACGGCCAccgacgccuggccc
((.(((.(((.(((..((.(((((..((((((.((((((...((....))..))))))))))))..))))).))...))).)))))).)).

Structure

-  g   c   c   -cA  U     CU      C      ccc  g 
 gg cag gcg cgg   CC UGGCU  AGACUG UUACUg   gg c
 || ||| ||| |||   || |||||  |||||| ||||||   ||  
 cc guc cgc gcc   GG ACUGA  UCUGAC AAUgac   cc c
c  g   -   a   ACC  C     CC      -      -uu  g 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context

chr11: 75173388-75173478 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from mmu-mir-212

Mature mmu-miR-212-5p

• Accession: MIMAT0017053
• Description: Mus musculus mmu-miR-212-5p mature miRNA
• Sequence: 16 - ACCUUGGCUCUAGACUGCUUACU - 38
• Evidence: experimental ; Illumina [5]

Mature mmu-miR-212-3p

• Accession: MIMAT0000659
• Description: Mus musculus mmu-miR-212-3p mature miRNA
• Sequence: 56 - UAACAGUCUCCAGUCACGGCCA - 77
• Evidence: experimental ; cloned [3], Illumina [4-5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12624257
   Vertebrate microRNA genes
   "Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP"
   "Science (2003) 299:1540


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


5. PubMed ID: 15634332
   New human and mouse microRNA genes found by homology search
   "Weber MJ"
   "FEBS J (2005) 272:59-73