miRBase entry: rno-mir-183

Stem-loop rno-mir-183


Accession
MI0000928
Description
Rattus norvegicus rno-mir-183 precursor miRNA
Gene family
MIPF0000066; mir-183

Literature search
35 open access papers mention rno-mir-183
(109 sentences)

Sequence

489895 reads, 834 reads per million, 491 experiments
ccagagagugugacuccuguccugugUAUGGCACUGGUAGAAUUCACUgugaacagucucggucagUGAAUUACCGAAGGGCCAUAAacagagcagagacagauccgcga
...(.(.((.((.(((.(((.((((.((((((.((((((..(((((((((((......)))..))))))))))))..)).)))))).)))).)))))).)).)).).)..

Structure
cca a a  g  a   c   c    g      A  --    GA        --   ac 
   g g gu ug cuc ugu cugu UAUGGC CU  GGUA  AUUCACUg  uga  a
   | | || || ||| ||| |||| |||||| ||  ||||  ||||||||  |||   
   c c ua ac gag acg gaca AUACCG GA  CCAU  UAAGUgac  gcu  g
-ag g c  g  a   -   a    A      G  AG    --        ug   cu 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context
chr4: 57463569-57463678 [-]
Clustered miRNAs
3 other miRNAs are < 10 kb from rno-mir-183
Name Accession Chromosome Start End Strand Confidence




Database links

Mature rno-miR-183-5p

Accession MIMAT0000860
Description Rattus norvegicus rno-miR-183-5p mature miRNA
Sequence 27 - UAUGGCACUGGUAGAAUUCACU - 48
Evidence experimental
cloned [1-2], SOLiD [3]

Mature rno-miR-183-3p

Accession MIMAT0017141
Description Rattus norvegicus rno-miR-183-3p mature miRNA
Sequence 67 - UGAAUUACCGAAGGGCCAUAA - 87
Evidence experimental
SOLiD [3]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 16766679
    Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
    "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
    "Genes Dev (2006) 20:1732-1743

  3. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249