Stem-loop sequence gga-let-7a-2

Accession

MI0001259 (change log)

Description

Gallus gallus let-7a-2 stem-loop

Gene family

MIPF0000002; let-7

Literature search

53 open access papers mention gga-let-7a-2
(267 sentences)

Stem-loop

      uu   g   u             uagaa ua a 
5' agg  gag uag agguuguauaguu     u  c c
   |||  ||| ||| |||||||||||||     |  | c
3' ucc  uuc auc uccaacaugucaa     a  g a
      -u   g   c             --uag gg a 

Deep sequencing

12645820 reads, 1.51e+05 reads per million, 5 experiments

Confidence

Annotation confidence: high

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Genome context

• Coordinates (Gallus_gallus-5.0; GCA_000002315.3): chr24: 3343196-3343267 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from gga-let-7a-2

• gga-mir-100: chr24: 3335097-3335176 [+]
• gga-mir-6675: chr24: 3341724-3341832 [+]
• gga-let-7a-2: chr24: 3343196-3343267 [+]

Database links

• EntrezGene:
• RNAcentral:URS000075EB66_9031
• miRBase Tracker:MI0001259

Mature sequence gga-let-7a-5p

• Accession: MIMAT0001101
• Sequence: 5 - ugagguaguagguuguauaguu - 26
• Deep sequencing: 38180273 reads, 5 experiments
• Evidence: experimental; cloned [2], Illumina [3]
• Database links:
  • RNAcentral:URS0000416056_9031
• Predicted targets:
  • TargetScanVert:gga-let-7a-5p
  • miRDB:gga-let-7a-5p

Mature sequence gga-let-7a-2-3p

• Accession: MIMAT0031037
• Sequence: 50 - cuguacaaccuccuagcuuucc - 71
• Deep sequencing: 282 reads, 5 experiments
• Evidence: experimental; Illumina [3]
• Predicted targets:
  • TargetScanVert:gga-let-7a-2-3p
  • miRDB:gga-let-7a-2-3p

References

1. PMID:15592404 "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution" International Chicken Genome Sequencing Consortium Nature. 432:695-716(2004).
2. PMID:18256158 "MicroRNA profile of Marek's disease virus-transformed T-cell line MSB-1: predominance of virus-encoded microRNAs" Yao Y, Zhao Y, Xu H, Smith LP, Lawrie CH, Watson M, Nair V J Virol. 82:4007-4015(2008).
3. " McBride D, Carre W, Law A, Clinton M Unpublished.
4. PMID:18256158 "MicroRNA profile of Marek's disease virus-transformed T-cell line MSB-1: predominance of virus-encoded microRNAs" Yao Y, Zhao Y, Xu H, Smith LP, Lawrie CH, Watson M, Nair V J Virol. 82:4007-4015(2008).
5. PMID:23034410 "Birth and expression evolution of mammalian microRNA genes" Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H Genome Res. 23:34-45(2013).