Stem-loop sequence dre-mir-221

Accession

MI0001387 (change log)

Description

Danio rerio miR-221 stem-loop

Gene family

MIPF0000051; mir-221

Literature search

10 open access papers mention dre-mir-221
(73 sentences)

Stem-loop

   -------------------   gu     ug   u         auuu     u     
5'                    guc  gaacc  gca acaauguag    cugug ggua 
                      |||  |||||  ||| |||||||||    ||||| ||| c
3'                    cgg  uuugg  cgu uguuacauc    gacau cuau 
   cucgucuuaauaagacgac   ac     gu   c         ----     -     

Deep sequencing

44269 reads, 1.87e+03 reads per million, 11 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCz11; GCA_000002035.4): chr9: 33920932-33921024 [-]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from dre-mir-221

• dre-mir-222a: chr9: 33921464-33921571 [-]
• dre-mir-221: chr9: 33920932-33921024 [-]

Database links

• EntrezGene:mir221
• RNAcentral:URS000075E98A_7955
• miRBase Tracker:MI0001387

Mature sequence dre-miR-221-5p

• Accession: MIMAT0031926
• Sequence: 8 - accuggcauacaauguagauuucugu - 33
• Deep sequencing: 7963 reads, 11 experiments
• Evidence: not experimental
• Database links:
  • RNAcentral:URS00003713CD_7955

Mature sequence dre-miR-221-3p

• Accession: MIMAT0001288
• Previous IDs: dre-miR-221
• Sequence: 48 - agcuacauugucugcuggguuuc - 70
• Deep sequencing: 36306 reads, 11 experiments
• Evidence: experimental; cloned [1-2]
• Database links:
  • RNAcentral:URS0000170CF4_7955
• Predicted targets:
  • TargetScanFish:dre-miR-221

References

1. PMID:12624257 "Vertebrate microRNA genes" Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP Science. 299:1540(2003).
2. PMID:15937218 "The developmental miRNA profiles of zebrafish as determined by small RNA cloning" Chen PY, Manninga H, Slanchev K, Chien M, Russo JJ, Ju J, Sheridan R, John B, Marks DS, Gaidatzis D, Sander C, Zavolan M, Tuschl T Genes Dev. 19:1288-1293(2005).