miRBase entry: hsa-mir-545

Stem-loop hsa-mir-545


Accession
MI0003516
Symbol
HGNC: MIR545
Description
Homo sapiens hsa-mir-545 precursor miRNA
Gene family
MIPF0000098; mir-95

Literature search
11 open access papers mention hsa-mir-545
(18 sentences)

Sequence

4665 reads, 223 reads per million, 57 experiments
cccagccuggcacauuaguaggccUCAGUAAAUGUUUAUUAGAUGAauaaaugaaugacucaUCAGCAAACAUUUAUUGUGUGCcugcuaaagugagcuccacagg
.....((((((((.((((((((((.((((((((((((.((.(((((.............))))))).)))))))))))).).))))))))).))).....).))))

Structure
cccag    - -----   a         - U            A  A     auaaa 
     ccug g     cac uuaguaggc c CAGUAAAUGUUU UU GAUGA     u
     |||| |     ||| ||||||||| | |||||||||||| || |||||     g
     ggac c     gug aaucgucCG G GUUAUUUACAAA GA CUacu     a
-----    a cucga   a         U U            C  -     cagua 


Annotation confidence High
Do you think this miRNA is real?
Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The 5' end of the miRNA may be offset with respect to previous annotations.

Genome context
chrX: 74287104-74287209 [-]
Clustered miRNAs
1 other miRNA is < 10 kb from hsa-mir-545
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-545 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-545-5p

Accession MIMAT0004785
Description Homo sapiens hsa-miR-545-5p mature miRNA
Sequence 25 - UCAGUAAAUGUUUAUUAGAUGA - 46
Evidence experimental
cloned [2]
Database links
Predicted targets

Mature hsa-miR-545-3p

Accession MIMAT0003165
Description Homo sapiens hsa-miR-545-3p mature miRNA
Sequence 63 - UCAGCAAACAUUUAUUGUGUGC - 84
Evidence experimental
cloned [1-2]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 16274478
    Identification of clustered microRNAs using an ab initio prediction method
    Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
    BMC Bioinformatics (2005) 6:267