Stem-loop sequence hsa-mir-574

Accession

MI0003581 (change log)

Symbol

HGNC:MIR574

Description

Homo sapiens miR-574 stem-loop

Gene family

MIPF0000419; mir-574

Literature search

96 open access papers mention hsa-mir-574
(437 sentences)

Stem-loop

   gggaccug g      c         a u                 ug  gc 
5'         c ugggug gggcgugug g gugugugugugagugug  uc  u
           | |||||| ||||||||| | |||||||||||||||||  ||   
3'         g acucac cccgcacac c cacacacguacucgcac  gg  c
   -------- g      a         - -                 cu  gc 

Deep sequencing

156655 reads, 781 reads per million, 166 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr4: 38868032-38868127 [+]
• Overlapping transcripts:

  intergenic

Database links

• EntrezGene:MIR574
• HGNC:MIR574
• RNAcentral:URS000075BE91_9606
• miRBase Tracker:MI0003581

Mature sequence hsa-miR-574-5p

• Accession: MIMAT0004795
• Sequence: 25 - ugagugugugugugugagugugu - 47
• Deep sequencing: 30638 reads, 165 experiments
• Evidence: experimental; cloned [2]
• Database links:
  • RNAcentral:URS000057466C_9606
• Predicted targets:
  • TargetMiner:hsa-miR-574-5p
  • TargetScanVert:hsa-miR-574-5p
  • miRDB:hsa-miR-574-5p
  • microrna.org:hsa-miR-574-5p

Mature sequence hsa-miR-574-3p

• Accession: MIMAT0003239
• Previous IDs: hsa-miR-574
• Sequence: 61 - cacgcucaugcacacacccaca - 82
• Deep sequencing: 125985 reads, 160 experiments
• Evidence: experimental; Microarray [1], RT-PCR [1], SAGE [1], cloned [2-3]
• Database links:
  • RNAcentral:URS00001CF056_9606
• Predicted targets:
  • TargetMiner:hsa-miR-574-3p
  • TargetScanVert:hsa-miR-574-3p
  • miRDB:hsa-miR-574-3p
  • microrna.org:hsa-miR-574-3p

References

1. PMID:16505370 "The colorectal microRNAome" Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE Proc Natl Acad Sci U S A. 103:3687-3692(2006).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:17616659 "Patterns of known and novel small RNAs in human cervical cancer" Lui WO, Pourmand N, Patterson BK, Fire A Cancer Res. 67:6031-6043(2007).