Stem-loop hsa-mir-574

Accession

MI0003581

Symbol

HGNC: MIR574

Description

Homo sapiens hsa-mir-574 precursor miRNA

Literature search

96 open access papers mention hsa-mir-574
(449 sentences)

Sequence

54104 reads, 461 reads per million, 144 experiments

gggaccugcgugggugcgggcgugUGAGUGUGUGUGUGUGAGUGUGUgucgcuccgggucCACGCUCAUGCACACACCCACAcgcccacacucagg
........(.((((((.(((((((((.(.(((((((((((((((((.(.(.(....)).)))))))))))))))))))))))))))).)))))).)

Structure

gggaccug g      c         A U                 U u g u 
        c ugggug gggcgugUG G GUGUGUGUGUGAGUGUG g c c c
        | |||||| ||||||||| | ||||||||||||||||| | | |  
        g acucac cccgcACAC C CACACACGUACUCGCAC c g g c
-------- g      a         - -                 - u - g 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr4: 38868032-38868127 [+]

Disease association

hsa-mir-574 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-574-5p

• Accession: MIMAT0004795
• Description: Homo sapiens hsa-miR-574-5p mature miRNA
• Sequence: 25 - UGAGUGUGUGUGUGUGAGUGUGU - 47
• Evidence: experimental ; cloned [2]

Mature hsa-miR-574-3p

• Accession: MIMAT0003239
• Description: Homo sapiens hsa-miR-574-3p mature miRNA
• Sequence: 61 - CACGCUCAUGCACACACCCACA - 82
• Evidence: experimental ; Microarray [1], RT-PCR [1], SAGE [1], cloned [2-3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 17616659
   Patterns of known and novel small RNAs in human cervical cancer
   "Lui WO, Pourmand N, Patterson BK, Fire A"
   "Cancer Res (2007) 67:6031-6043


3. PubMed ID: 16505370
   The colorectal microRNAome
   "Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE"
   "Proc Natl Acad Sci U S A (2006) 103:3687-3692