miRBase entry: hsa-mir-548d-2

Stem-loop hsa-mir-548d-2


Accession
MI0003671
Symbol
HGNC: MIR548D2
Description
Homo sapiens hsa-mir-548d-2 precursor miRNA
Gene family
MIPF0000317; mir-548

Literature search
58 open access papers mention hsa-mir-548d-2
(278 sentences)

Sequence

4216 reads, 206 reads per million, 88 experiments
gagagggaagauuuagguuggugcAAAAGUAAUUGUGGUUUUUGCCauugaaaguaauggCAAAAACCACAGUUUCUUUUGCaccaaccuaauaaaa
............(((((((((((((((((.((((((((((((((((((((....)))))))))))))))))))).))))))))))))))))).....

Structure
gagagggaagau                 U                    a 
            uuagguuggugcAAAAG AAUUGUGGUUUUUGCCauug a
            ||||||||||||||||| ||||||||||||||||||||  
            aauccaaccaCGUUUUC UUGACACCAAAAACgguaau a
-------aaaau                 U                    g 


Annotation confidence High
Do you think this miRNA is real?

Genome context
chr17: 67471489-67471585 [-]
Clustered miRNAs
1 other miRNA is < 10 kb from hsa-mir-548d-2
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-548d-2 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-548d-5p

Accession MIMAT0004812
Description Homo sapiens hsa-miR-548d-5p mature miRNA
Sequence 25 - AAAAGUAAUUGUGGUUUUUGCC - 46
Evidence experimental
cloned [2]
Database links
Predicted targets

Mature hsa-miR-548d-3p

Accession MIMAT0003323
Description Homo sapiens hsa-miR-548d-3p mature miRNA
Sequence 61 - CAAAAACCACAGUUUCUUUUGC - 82
Evidence experimental
RT-PCR [1], SAGE [1], cloned [2]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 16505370
    The colorectal microRNAome
    "Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE"
    "Proc Natl Acad Sci U S A (2006) 103:3687-3692