Stem-loop rno-mir-378a

Accession

MI0003719

Description

Rattus norvegicus rno-mir-378a precursor miRNA

Gene family

MIPF0000168; mir-378

Literature search

27 open access papers mention rno-mir-378a
(120 sentences)

Sequence

11321237 reads, 9439 reads per million, 508 experiments

gggCUCCUGACUCCAGGUCCUGUGUguuaccucgaaauagcACUGGACUUGGAGUCAGAAGGccu
((.((.((((((((((((((.((((..(........)..)))).)))))))))))))).)).)).

Structure

-  g  C              U    gu acc 
 gg CU CUGACUCCAGGUCC GUGU  u   u
 || || |||||||||||||| ||||  |    
 cc GA GACUGAGGUUCAGG CAcg  a   c
u  G  A              U    au aag 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context

chr18: 56726150-56726214 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from rno-mir-378a

Mature rno-miR-378a-5p

• Accession: MIMAT0003378
• Description: Rattus norvegicus rno-miR-378a-5p mature miRNA
• Sequence: 4 - CUCCUGACUCCAGGUCCUGUGU - 25
• Evidence: experimental ; SOLiD [3]

Mature rno-miR-378a-3p

• Accession: MIMAT0003379
• Description: Rattus norvegicus rno-miR-378a-3p mature miRNA
• Sequence: 42 - ACUGGACUUGGAGUCAGAAGG - 62
• Evidence: experimental ; cloned [1-2], Northern [1], SOLiD [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16766679
   Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
   "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
   "Genes Dev (2006) 20:1732-1743


3. PubMed ID: 20403161
   Small RNA expression and strain specificity in the rat
   Linsen SE, de Wit E, de Bruijn E, Cuppen E
   BMC Genomics (2010) 11:249