miRBase entry: bta-mir-29a

Stem-loop bta-mir-29a


Accession
MI0004733
Description
Bos taurus bta-mir-29a precursor miRNA
Gene family
MIPF0000009; mir-29

Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?

Bta-mir-29a is a microRNA that has been studied in various contexts. It has been found to be expressed at relatively higher levels in the ovarian cortical portion, with higher expression in the adult ovarian cortex compared to the fetal ovary [PMC2762473]. Bta-mir-29a has also been investigated as a potential internal control miRNA in bovine milk sEVs for normalization in qPCR [PMC9961204]. In addition, it has been identified as one of the miRNAs associated with uterine proteins and exhibited a strong and positive association with SUGT1 and PPID [PMC8273763]. Bta-mir-29a has also shown different abundance levels in pregnant vs. non-pregnant cows, with higher abundance levels observed in cows that reached term [PMC5662615]. Furthermore, it has been found to be negatively correlated with lysosome expression [PMC9378797]. Overall, bta-mir-29a is a microRNA that plays a role in ovarian development, pregnancy, and uterine protein regulation. It is also being investigated for its potential use as an internal control miRNA and its association with lysosome expression.

Literature search
31 open access papers mention bta-mir-29a
(133 sentences)

Sequence

151250 reads, 1228 reads per million, 76 experiments
augacugauuucuuuugguguucagagucaauauaauuuuCUAGCACCAUCUGAAAUCGGUUAu
((((((((((((...(((((((.((((...........)))))))))))...))))))))))))

Structure
            uuu       c    ucaa 
augacugauuuc   ugguguu agag    u
||||||||||||   ||||||| ||||    a
uAUUGGCUAAAG   ACCACGA UCuu    u
            UCU       -    uuaa 


Annotation confidence High
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Genome context
chr4: 95726868-95726931 [-]
Clustered miRNAs
1 other miRNA is < 10 kb from bta-mir-29a
Name Accession Chromosome Start End Strand Confidence




Database links

Mature bta-miR-29a

Accession MIMAT0003518
Description Bos taurus bta-miR-29a mature miRNA
Sequence 41 - CUAGCACCAUCUGAAAUCGGUUA - 63
Evidence experimental
cloned [1-2]

References

  1. PubMed ID: 17105755
    Discovery and profiling of bovine microRNAs from immune-related and embryonic tissues
    "Coutinho LL, Matukumalli LK, Sonstegard TS, Van Tassell CP, Gasbarre LC, Capuco AV, Smith TP"
    "Physiol Genomics (2007) 29:35-43

  2. PubMed ID: 17306260
    Identification and characterization of microRNAs from the bovine adipose tissue and mammary gland
    "Gu Z, Eleswarapu S, Jiang H"
    "FEBS Lett (2007) 581:981-988