Accession
MI0006394
Symbol
HGNC:
MIR1260A
Description
Homo sapiens
hsa-mir-1260a precursor miRNA
Gene family
MIPF0001020;
mir-1260a
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR1260A is a microRNA that has been found to be significant in certain contexts. In a study, it was observed that MIR1260A and mir93.3p became significant when women with male factor infertility were omitted, suggesting that these microRNAs may be markers of pre-existing pathologies [PMC9580729]. Further analysis of MIR1260A's gene targets revealed that it had 42 common gene targets when compared with gene target lists from miRTarBase and TargetScan [PMC8504092]. These common gene targets were found to have significant interactions at the protein level [PMC8504092]. Additionally, the study suggested that MIR1260A and miR1260b, which were found to be differentiated in peripheral blood, could serve as prognostic bioindicators [PMC8504092]. The higher expression level of MIR1260A and miR-1260b was also reported in the serum and FFPE tissues of prostate cancer patients [PMC8504092]. In patients who received no chemotherapy, the expression level of MIR1260A was found to have both increased and decreased [PMC8504092]. Furthermore, in a different study, it was observed that on day 7, both MIR1260A and miR1260b were downregulated compared to baseline samples in certain groups [PMC7169272]. Overall, these findings highlight the significance of MIR1260A in various contexts.
Literature search
23 open access papers mention hsa-mir-1260a
(58 sentences)
(58 sentences)
Sequence
529
reads,
892
reads per million, 28 experiments
accuuuccagcucAUCCCACCUCUGCCACCAaaacacucaucgcggggucagagggagugccaaaaaagguaa
((((((...((.(.((((...((((((.((..............)))).))))))))).))....))))))..
((((((...((.(.((((...((((((.((..............)))).))))))))).))....))))))..
Structure
-- -cca u A ACC - A Aaaaca accuuu gc c UCCC UCUG CC CC c |||||| || | |||| |||| || || uggaaa cg g aggg agac gg gg u aa aaac u - --- u - cgcuac
Annotation confidence
Not enough data
Do you think this miRNA is real?
Genome context
chr14: 77266218-77266290 [+]
Disease association
hsa-mir-1260a is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-1260a
| Accession | MIMAT0005911 |
| Description | Homo sapiens hsa-miR-1260a mature miRNA |
| Sequence | 14 - AUCCCACCUCUGCCACCA - 31 |
| Evidence |
experimental
Illumina [1] |
| Database links |
|
| Predicted targets |
|
References
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