4 publications mentioning rno-mir-341

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-341. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1

For example, the regulation of NF-κB activation in vivo by PRKCZ (network 1) [32] is related to the downregulated miR-148b, and the downregulation of miR-133b and miR-341 is related to PTPRF (Figure 7, networks 1 and 4), the overexpression of which induces apoptosis independently of p53 through a caspase cascade that does not affect cell adhesion [33].

2

The intensities are in the middle range except for miR-341, which is expressed at a low level (data not shown).

Secondly, array data showed differential regulation of miR-341; however, the mature miR-341 species was not detected on multiple northern blots, whereas high signal intensities were observed for pri-miR-341 or pre-miR-341 (Fig. S2).

We used northern blot analysis to verify the array results and to visualize the presence of pri-, pre- and mature miRNA (Fig. 2), which revealed mature miRNA for all the analyzed miRNA except miR-341.

Because only pre-miR-341 was detectable by northern blotting, it was eliminated from further analysis (for images of whole blots see Fig. S2).

3

control Function rno-miR-653-3p 37.56097561 Unknown rno-miR-3594-3p 9.31358885 Unknown rno-miR-483-3p 8.414634146 Anti-apoptotic oncogene, cardiovascular inflammation and remo delling rno-miR-92b-5p 8.096126255 Heart development and atrial fibrillation rno-miR-377-5p 4.84735544 Atrial fibrillation and structural remo delling rno-miR-341 4.764878049 Atrial fibrillation and TGF-β/Smad2/3 pathway rno-miR-21-3p 4.637785208 Cell proliferation and invasion.

4

miR-125b, miR-146, miR-150, miR-199a, miR-21, miR-129, miR-341 and miR-451 have been confirmed to play an important role in the different developmental stages of the cardiovascular system (4– 18).