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6 publications mentioning dre-mir-15b

Open access articles that are associated with the species Danio rerio and mention the gene name mir-15b. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 14
Finally, the upregulation of the miR-15 family has been suggested to be a key regulatory event linked to the terminal exit of cardiomyocytes from cell cycle during the post-natal period [119]. [score:5]
Not surprisingly, considering the prominent role played by miRs in the regulation of this switch, Porrello and colleagues [143] have recently shown that inhibition of the miR-15 family can increase proliferation in the adult mouse heart, leading to improved cardiac function after injury. [score:4]
Porrello E. R. Mahmoud A. I. Simpson E. Johnson B. A. Grinsfelder D. Canseco D. Mammen P. P. Rothermel B. A. Olson E. N. Sadek H. A. Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family Proc. [score:2]
Porrello E. R. Johnson B. A. Aurora A. B. Simpson E. Nam Y. J. Matkovich S. J. Dorn G. W. van Rooij E. Olson E. N. miR-15 family regulates postnatal mitotic arrest of cardiomyocytes Circ. [score:2]
Examples include the let-7 family, which contains the first miRNA to ever be described [59] or the miR-1/133 and miR-15 families. [score:1]
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2
[+] score: 12
Ovine cardiac expression of miR-15a expression was lowest at 140 days gestation and highest at 21 days of age (P < 0.05), the expression of miR-15b was lowest at 173 days of age and highest at 5 days of age (P < 0.05) and miR-195 expression was lowest at 140 days gestation and highest at 91 days gestation, 5 and 21 days of age (P < 0.05). [score:9]
miR-15 family. [score:1]
members miR-15b, miR-16, miR-195 and miR-497 were identified in Clusters 5, 2, 1 and 4, respectively. [score:1]
The relative expression of (MS00031423, QIAGEN Pty Ltd, Doncaster, Australia), the (miR-15a, MS00008785; miR-15b, MS00008799; miR-16, MS00031493; miR-195, MS00008953; miR-497, MS00031906; QIAGEN Pty Ltd, Doncaster, Australia), miR-199a (MS00007602; QIAGEN Pty Ltd, Doncaster, Australia) and miR-590 (MS00010269; QIAGEN Pty Ltd, Doncaster, Australia) were measured using quantitative real-time reverse transcription PCR (qRT-PCR) on an ABI ViiA7 (PE Applied Biosystems, Foster City, CA). [score:1]
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3
[+] score: 10
Fibroblast growth factor-2 (FGF-2), identified as a miR-15b target gene, was decreased at the protein expression levels in response to morphine. [score:5]
Dave and Khalili, 2010 reported that in human monocyte-derived macrophages treated with morphine, miR-15b expression levels were greatly increased. [score:3]
Later studies have shown that morphine induces inflammation and oxidative stress in immune cells through regulating the miR-15b and 181b, thereby contributing to expansion of the HIV-1 CNS reservoir and hence to AIDS progression. [score:2]
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4
[+] score: 10
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-17, hsa-mir-18a, hsa-mir-19a, hsa-mir-19b-1, hsa-mir-20a, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-27a, hsa-mir-92a-1, hsa-mir-92a-2, mmu-let-7g, mmu-let-7i, mmu-mir-1a-1, mmu-mir-15b, mmu-mir-23b, mmu-mir-27b, mmu-mir-130a, mmu-mir-133a-1, mmu-mir-140, mmu-mir-24-1, hsa-mir-196a-1, mmu-mir-199a-1, hsa-mir-199a-1, mmu-mir-200b, mmu-mir-206, hsa-mir-30c-2, hsa-mir-196a-2, hsa-mir-199a-2, hsa-mir-199b, hsa-mir-200b, mmu-mir-301a, mmu-let-7d, hsa-let-7g, hsa-let-7i, hsa-mir-1-2, hsa-mir-15b, hsa-mir-23b, hsa-mir-27b, hsa-mir-130a, hsa-mir-133a-1, hsa-mir-133a-2, hsa-mir-140, hsa-mir-206, mmu-mir-30c-1, mmu-mir-30c-2, mmu-mir-196a-1, mmu-mir-196a-2, mmu-mir-200a, mmu-let-7a-1, mmu-let-7a-2, mmu-let-7b, mmu-let-7c-1, mmu-let-7c-2, mmu-let-7e, mmu-let-7f-1, mmu-let-7f-2, mmu-mir-15a, mmu-mir-18a, mmu-mir-20a, mmu-mir-24-2, mmu-mir-27a, mmu-mir-92a-2, hsa-mir-200c, hsa-mir-1-1, mmu-mir-1a-2, mmu-mir-17, mmu-mir-19a, mmu-mir-200c, mmu-mir-199a-2, mmu-mir-199b, mmu-mir-19b-1, mmu-mir-92a-1, hsa-mir-30c-1, hsa-mir-200a, hsa-mir-301a, mmu-mir-133a-2, mmu-mir-133b, hsa-mir-133b, hsa-mir-196b, mmu-mir-196b, dre-mir-196a-1, dre-mir-199-1, dre-mir-199-2, dre-mir-199-3, hsa-mir-18b, dre-let-7a-1, dre-let-7a-2, dre-let-7a-3, dre-let-7a-4, dre-let-7a-5, dre-let-7a-6, dre-let-7b, dre-let-7c-1, dre-let-7c-2, dre-let-7d-1, dre-let-7d-2, dre-let-7e, dre-let-7f, dre-let-7g-1, dre-let-7g-2, dre-let-7h, dre-let-7i, dre-mir-1-2, dre-mir-1-1, dre-mir-15a-1, dre-mir-15a-2, dre-mir-17a-1, dre-mir-17a-2, dre-mir-18a, dre-mir-18b, dre-mir-18c, dre-mir-19a, dre-mir-20a, dre-mir-23b, dre-mir-24-4, dre-mir-24-2, dre-mir-24-3, dre-mir-24-1, dre-mir-27a, dre-mir-27b, dre-mir-27c, dre-mir-27d, dre-mir-27e, dre-mir-30c, dre-mir-92a-1, dre-mir-92a-2, dre-mir-92b, dre-mir-130a, dre-mir-133a-2, dre-mir-133a-1, dre-mir-133b, dre-mir-133c, dre-mir-140, dre-mir-196a-2, dre-mir-196b, dre-mir-200a, dre-mir-200b, dre-mir-200c, dre-mir-206-1, dre-mir-206-2, dre-mir-301a, dre-let-7j, hsa-mir-92b, mmu-mir-666, mmu-mir-18b, mmu-mir-92b, mmu-mir-1b, dre-mir-196c, dre-mir-196d, mmu-mir-3074-1, mmu-mir-3074-2, hsa-mir-3074, mmu-mir-133c, mmu-let-7j, mmu-let-7k, dre-mir-24b
miRNA Embryonic age Expression profile mir15a 48 and 72 hpf Midbrain, MHB, notochord mir15b 48 and 72 hpf Midbrain, neurocranium, notochord mir23b 30, 48, and 72 hpf Somites, lens, pharyngeal arches, notochord mir27b 48 and 72 hpf mir30c 48 and 72 hpf Brain, neurocranium, eye, heart mir130a 48 and 72 hpf Brain, gut tube, heart, eye mir133b 30, 48, and 72 hpf Notochord mir301a 48 and 72 hpf Forming cartilage Midbrain, neurocranium, eye, trigeminal ganglia Figure 5 Expression of mir23b in zebrafish embryos. [score:5]
miRNA Embryonic age Expression profile mir15a 48 and 72 hpf Midbrain, MHB, notochord mir15b 48 and 72 hpf Midbrain, neurocranium, notochord mir23b 30, 48, and 72 hpf Somites, lens, pharyngeal arches, notochord mir27b 48 and 72 hpf mir30c 48 and 72 hpf Brain, neurocranium, eye, heart mir130a 48 and 72 hpf Brain, gut tube, heart, eye mir133b 30, 48, and 72 hpf Notochord mir301a 48 and 72 hpf Forming cartilage Midbrain, neurocranium, eye, trigeminal ganglia Figure 5 Expression of mir23b in zebrafish embryos. [score:5]
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5
[+] score: 5
For example, miR-590 and miR-17/92 clusters promote cardiomyocyte proliferation by inhibiting the proliferation repressors Homer protein homolog 1 (Homer1) and Homeodomain-only protein x (Hopx), whereas miR-15 family represses cardiomyocyte proliferation by inhibiting the proliferative activator Checkpoint kinase 1 (Check1). [score:5]
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6
[+] score: 1
Notably, nearly all of the identified miRNA seed families have been previously associated with cancer, in some cases causally, e. g. loss of miR-15 and miR-16 [87]. [score:1]
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