| 1 |
[+]
score:
5
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, mmu-let-7g, mmu-let-7i, mmu-let-7d, hsa-let-7g, hsa-let-7i, mmu-let-7a-1, mmu-let-7a-2, mmu-let-7b, mmu-let-7c-1, mmu-let-7c-2, mmu-let-7e, mmu-let-7f-1, mmu-let-7f-2, eca-let-7a, eca-let-7e, eca-let-7g, eca-let-7d, eca-let-7f, eca-let-7c, mmu-let-7j, mmu-let-7k, chi-let-7a, chi-let-7b, chi-let-7c, chi-let-7d, chi-let-7e, chi-let-7f, chi-let-7g, chi-let-7i, ocu-let-7a-1, ocu-let-7a-2, ocu-let-7a-3, ocu-let-7b, ocu-let-7c, ocu-let-7d, ocu-let-7f-1, ocu-let-7f-2, ocu-let-7g, ocu-let-7i
It inhibits the processing of microRNAs (miRNAs) into mature miRNAs by binding to the terminal loops of miRNA precursors such as let-7 family members [6].
[score:3]
The let-7 family of microRNAs.
[score:1]
Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing.
[score:1]
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| 2 |
[+]
score:
5
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-21, hsa-mir-30a, hsa-mir-30c-2, hsa-mir-30d, hsa-let-7g, hsa-let-7i, hsa-mir-30b, hsa-mir-30c-1, hsa-mir-30e, eca-mir-30c, eca-mir-30e, eca-let-7a, eca-mir-30b, eca-mir-30d, eca-let-7e, eca-mir-21, eca-let-7g, eca-mir-30c-2, eca-let-7d, eca-let-7f, eca-let-7c
In the present study, two members of the let-7 family of miRNAs, let-7d-3p and let-7d-5p, and miR-21-5p had increased expression following exercise.
[score:3]
The Let-7 family of miRNAs are involved in the regulation of glucose homeostasis and insulin sensitivity [43], both key processes in energy metabolism during exercise.
[score:2]
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| 3 |
[+]
score:
5
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-16-1, hsa-mir-19b-1, hsa-mir-19b-2, hsa-mir-28, hsa-mir-92a-1, hsa-mir-92a-2, hsa-mir-103a-2, hsa-mir-103a-1, hsa-mir-107, hsa-mir-16-2, hsa-mir-197, hsa-mir-148a, hsa-mir-30d, hsa-mir-7-1, hsa-mir-7-2, hsa-mir-7-3, hsa-mir-215, hsa-mir-221, hsa-let-7g, hsa-let-7i, hsa-mir-15b, hsa-mir-128-1, hsa-mir-140, hsa-mir-125a, hsa-mir-155, hsa-mir-128-2, hsa-mir-361, hsa-mir-148b, hsa-mir-423, hsa-mir-425, hsa-mir-451a, hsa-mir-486-1, hsa-mir-744, hsa-mir-103b-1, hsa-mir-103b-2, eca-mir-107b, eca-mir-7-1, eca-mir-140, eca-mir-148a, eca-mir-15b, eca-mir-16-1, eca-mir-197, eca-mir-148b, eca-let-7a, eca-mir-7-2, eca-mir-30d, eca-let-7e, eca-mir-125a, eca-mir-423, eca-mir-451, eca-mir-107a, eca-let-7g, eca-mir-128-1, eca-mir-191a, eca-mir-15a, eca-mir-16-2, eca-mir-19b, eca-mir-92a, eca-mir-128-2, eca-mir-28, eca-mir-103, eca-let-7d, eca-let-7f, eca-mir-7-3, eca-let-7c, eca-mir-155, eca-mir-486, eca-mir-215, eca-mir-221, eca-mir-361, hsa-mir-451b, hsa-mir-486-2, eca-mir-744, eca-mir-7177b, eca-mir-425
Koh W. Sheng C. T. Tan B. Lee Q. Y. Kuznetsov V. Kiang L. S. Tanavde V. Analysis of deep sequencing microRNA expression profile from human embryonic stem cells derived mesenchymal stem cells reveals possible role of let-7 microRNA family in downstream targeting of hepatic nuclear factor 4 alphaBMC Genom.
[score:5]
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| 4 |
[+]
score:
2
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-21, hsa-mir-26a-1, hsa-mir-26b, hsa-let-7g, hsa-let-7i, hsa-mir-143, hsa-mir-154, hsa-mir-26a-2, hsa-mir-377, gga-let-7i, gga-let-7a-3, gga-let-7b, gga-let-7c, gga-mir-26a, gga-let-7g, gga-let-7d, gga-let-7f, gga-let-7a-1, gga-let-7a-2, gga-let-7j, gga-let-7k, ssc-mir-26a, ssc-let-7c, ssc-let-7f-1, ssc-let-7i, ssc-mir-21, hsa-mir-494, bta-mir-26a-2, bta-let-7f-2, bta-mir-21, bta-mir-26b, gga-mir-21, bta-let-7d, bta-let-7g, bta-let-7a-1, bta-let-7f-1, bta-let-7i, bta-let-7a-2, bta-let-7a-3, bta-let-7b, bta-let-7c, bta-let-7e, bta-mir-143, bta-mir-154a, bta-mir-26a-1, bta-mir-377, bta-mir-494, eca-mir-26a, eca-let-7a, eca-let-7e, eca-mir-21, eca-mir-143, eca-let-7g, eca-mir-26a-2, eca-let-7d, eca-let-7f, eca-mir-154a, eca-mir-377, eca-mir-494, eca-let-7c, ssc-let-7a-1, ssc-let-7e, ssc-let-7g, ssc-mir-143, ssc-mir-494, bta-mir-26c, ssc-let-7a-2, ssc-let-7d, ssc-let-7f-2, bta-mir-154c, bta-mir-154b, eca-mir-154b, gga-mir-26a-2, ssc-mir-26b, gga-mir-143, gga-let-7l-1, gga-let-7l-2
The discovery of the regulatory miRNA let-7 in C. elegans in 2000 [10], with homologs in other species including humans, caused researchers to reconsider the idea that miRNAs may have a more widespread function within cells.
[score:2]
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| 5 |
[+]
score:
1
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-21, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-92a-1, hsa-mir-92a-2, hsa-mir-103a-2, hsa-mir-103a-1, hsa-mir-223, hsa-let-7g, hsa-let-7i, hsa-mir-1-2, hsa-mir-122, hsa-mir-140, hsa-mir-1-1, hsa-mir-486-1, hsa-mir-103b-1, hsa-mir-103b-2, eca-mir-140, eca-let-7a, eca-mir-24-1, eca-mir-1-1, eca-mir-122, eca-let-7e, eca-mir-21, eca-let-7g, eca-mir-191a, eca-mir-92a, eca-mir-1-2, eca-mir-103, eca-let-7d, eca-let-7f, eca-mir-24-2, eca-let-7c, eca-mir-486, eca-mir-223, hsa-mir-486-2
This suggests that the 10 most abundant plasma miRNA species did not belong to the abundant miRNA group in non-plasma tissues, except for the eca-let-7 family species (S4 Table).
[score:1]
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