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3 publications mentioning ssc-mir-4332

Open access articles that are associated with the species Sus scrofa and mention the gene name mir-4332. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 19
The genes FASN, SCD, and ESR1, which function to promote lipogenesis, may be regulated by miRNAs with downregulated expression in the DSP-TP, miR-4332, miR-182, miR-92b-3p, and miR-29c, which was coincident with the regulatory mechanism between gene expression and miRNA. [score:10]
In the regulatory networks of lipid deposition, several important lipogenic DEGs, FASN, SCD, and ESR1 were regulated by miR-4332, miR-182, miR-92b-3p, and miR-29c, respectively. [score:3]
The expressions of five genes (IRS1, CARNS1, MYOZ2, ANKRD2, and PLIN2) and four miRNAs (miR-4332, miR-451, miR-196a, and miR-29b) were significantly different between the DSP and the YY (S5 and S6 Figs). [score:3]
Some DE miRNAs, such as miR-29b, miR-122, miR-145-5p, let-7c, miR-4332, miR-182, miR-92b-3p, miR-29c,let-7a, and let-7e, and some DEGs such as CAV2, MYOZ2, FRZB, FASN, SCD, ESR1, and ADORA1, may be factors in the regulation of muscle growth and lipid deposition. [score:2]
Based on the fold change, the top five were miR-4332 (FC = 0.024), miR-29b (FC = 0.140), miR-92b-3p (FC = 0.183), miR-362 (FC = 5.406), and miR-122 (FC = 0.193). [score:1]
[1 to 20 of 5 sentences]
[+] score: 11
Unfortunately, 10 miRNAs including 4 up-regulated (miR-129*, miR-1343, miR-193b* and miR-590) and 6 down-regulated (miR-2887, miR-2904, miR-2904-3p, miR-4332-3p, miR-4332-5p and miR-739) do not have orthologous genes in human, so they do not have target genes in the database. [score:9]
Among the 40 DEMs obtained by deep sequencing, 8 (miR-100, miR-140, miR-184, miR-193a-5p, miR-222, miR-4332-3p, miR-451, and miR-574) were detectable in microarray. [score:1]
The fold changes of these miRNAs, except miR-4332-3p, were consistent between the two methods, but only miR-184 and miR-193a-5p were also identified as DEMs by microarray. [score:1]
[1 to 20 of 3 sentences]
[+] score: 5
Correspondingly, the most down-regulated microRNAs were ssc-miR-4332 (log [2]FC = -4.19), ssc-miR-374b-3p (log [2]FC = -6.07) and ssc-miR-95 (log [2]FC = -2.96). [score:4]
Among them, six microRNAs (ssc-miR-128, ssc-miR-186, ssc-miR-4332, ssc-miR-218-3p, ssc-miR-2320-5p and ssc-miR-150) were predicted to bind to the 3′UTR of WUH3 PRRSV genome. [score:1]
[1 to 20 of 2 sentences]