miRNA Search Results

sort by 2 publications mentioning hco-lin-4 Open access articles that are associated with the species Haemonchus contortus and mention the gene name lin-4. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.
1	[+] score: 6 Other miRNAs from this paper: cel-let-7, cel-lin-4, cel-mir-1, cel-mir-2, cel-mir-35, cel-mir-36, cel-mir-42, cel-mir-45, cel-mir-48, cel-mir-50, cel-mir-51, cel-mir-56, cel-mir-58a, cel-mir-63, cel-mir-71, cel-mir-72, cel-mir-81, cel-mir-82, cel-mir-84, cel-mir-86, cel-mir-124, cel-mir-228, cel-mir-241, cel-mir-250, cel-mir-265, cel-mir-273, cel-mir-58b, hco-mir-63a, hco-mir-50, hco-mir-250, hco-mir-5894a, hco-mir-124, hco-mir-45, hco-mir-86, hco-mir-71, hco-mir-84a, hco-mir-5352, hco-mir-7, hco-mir-228, hco-mir-5894b, hco-mir-1, hco-mir-2, hco-mir-63b, hco-mir-5983, hco-mir-72, hco-mir-190, hco-mir-84b, hco-mir-265, cel-mir-58c Of the highly expressed miRNAs common to both parasites, five (lin-4, mir-45, mir-50, mir-71, mir-228) are shared with C. elegans, where all except mir-50 are also abundant (using the same read number criteria) [42]. [score:3] Genetic analysis in the free-living nematode Caenorhabditis elegans led to the discovery of the first miRNA, lin-4, which controls hypodermal cell fate decisions during early larval development [17, 18]. [score:2] For both B. pahangi and H. contortus, lin-4 was found at higher abundance in L3 of both species compared to adult worms, a profile similar, but not identical, to the lin-4 expression profile in C. elegans. [score:1] [1 to 20 of 3 sentences]
2	[+] score: 4 Other miRNAs from this paper: oar-let-7b, oar-let-7c, hco-mir-5885a, hco-mir-40b, hco-mir-50, hco-mir-61, hco-mir-43, hco-mir-5895, hco-mir-45, hco-mir-5899, hco-mir-87a, hco-mir-87b, hco-mir-83, hco-mir-71, hco-mir-5908, hco-mir-84a, hco-mir-5352, hco-mir-228, hco-mir-5885b, hco-mir-5960, hco-mir-60, hco-mir-5885c, oar-let-7a, oar-let-7d, oar-let-7f, oar-let-7g, oar-let-7i, oar-mir-103, oar-mir-26a In the L4 libraries, hco-miR-5885a-3p, hco-miR-5885b-3p, hco-miR-5885c-3p, hco-miR-5908-3p, hco-lin-4-5p, hco-miR-83-3p and sequences homologous to cel-let-7-5p and asu-miR-100a-5p, not previously identified from H. contortus, are all highly expressed in the L4 EV-enriched and have lower read counts in the L4 EV -depleted libraries. [score:3] Interestingly a number of these (asu- miR-100a-5p, miR-60-3p, miR-71-5p, let-7-5p, lin-4-5p and miR-5885a, b, c-3p) were also present in EV libraries prepared from H. polygyrus adult stage [9], while miR-100a-5p and let-7-5p were recently identified in adult EV of the clade I nematode Trichuris muris [21]. [score:1] [1 to 20 of 2 sentences]

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2 publications mentioning hco-lin-4

Open access articles that are associated with the species Haemonchus contortus and mention the gene name lin-4. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 6

Of the highly expressed miRNAs common to both parasites, five (lin-4, mir-45, mir-50, mir-71, mir-228) are shared with C. elegans, where all except mir-50 are also abundant (using the same read number criteria) [42]. [score:3]

Genetic analysis in the free-living nematode Caenorhabditis elegans led to the discovery of the first miRNA, lin-4, which controls hypodermal cell fate decisions during early larval development [17, 18]. [score:2]

For both B. pahangi and H. contortus, lin-4 was found at higher abundance in L3 of both species compared to adult worms, a profile similar, but not identical, to the lin-4 expression profile in C. elegans. [score:1]

[1 to 20 of 3 sentences]

[+] score: 4

Other miRNAs from this paper: oar-let-7b, oar-let-7c, hco-mir-5885a, hco-mir-40b, hco-mir-50, hco-mir-61, hco-mir-43, hco-mir-5895, hco-mir-45, hco-mir-5899, hco-mir-87a, hco-mir-87b, hco-mir-83, hco-mir-71, hco-mir-5908, hco-mir-84a, hco-mir-5352, hco-mir-228, hco-mir-5885b, hco-mir-5960, hco-mir-60, hco-mir-5885c, oar-let-7a, oar-let-7d, oar-let-7f, oar-let-7g, oar-let-7i, oar-mir-103, oar-mir-26a

In the L4 libraries, hco-miR-5885a-3p, hco-miR-5885b-3p, hco-miR-5885c-3p, hco-miR-5908-3p, hco-lin-4-5p, hco-miR-83-3p and sequences homologous to cel-let-7-5p and asu-miR-100a-5p, not previously identified from H. contortus, are all highly expressed in the L4 EV-enriched and have lower read counts in the L4 EV -depleted libraries. [score:3]

Interestingly a number of these (asu- miR-100a-5p, miR-60-3p, miR-71-5p, let-7-5p, lin-4-5p and miR-5885a, b, c-3p) were also present in EV libraries prepared from H. polygyrus adult stage [9], while miR-100a-5p and let-7-5p were recently identified in adult EV of the clade I nematode Trichuris muris [21]. [score:1]

[1 to 20 of 2 sentences]

miRBase

2 publications mentioning hco-lin-4