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5 publications mentioning mdm-MIR828b

Open access articles that are associated with the species Malus domestica and mention the gene name MIR828b. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 270
Other miRNAs from this paper: mdm-MIR156a, mdm-MIR156b, mdm-MIR156c, mdm-MIR156d, mdm-MIR156e, mdm-MIR156f, mdm-MIR156g, mdm-MIR156h, mdm-MIR156i, mdm-MIR156j, mdm-MIR156k, mdm-MIR156l, mdm-MIR156m, mdm-MIR156n, mdm-MIR156o, mdm-MIR156p, mdm-MIR156q, mdm-MIR156r, mdm-MIR156s, mdm-MIR156t, mdm-MIR156u, mdm-MIR156v, mdm-MIR156w, mdm-MIR156x, mdm-MIR156y, mdm-MIR156z, mdm-MIR156aa, mdm-MIR156ab, mdm-MIR156ac, mdm-MIR156ad, mdm-MIR156ae, mdm-MIR159a, mdm-MIR159b, mdm-MIR162a, mdm-MIR162b, mdm-MIR164a, mdm-MIR164b, mdm-MIR164c, mdm-MIR164d, mdm-MIR164e, mdm-MIR164f, mdm-MIR167a, mdm-MIR167b, mdm-MIR167c, mdm-MIR167d, mdm-MIR167e, mdm-MIR167f, mdm-MIR167g, mdm-MIR167h, mdm-MIR167i, mdm-MIR167j, mdm-MIR168a, mdm-MIR168b, mdm-MIR172a, mdm-MIR172b, mdm-MIR172c, mdm-MIR172d, mdm-MIR172e, mdm-MIR172f, mdm-MIR172g, mdm-MIR172h, mdm-MIR172i, mdm-MIR172j, mdm-MIR172k, mdm-MIR172l, mdm-MIR172m, mdm-MIR172n, mdm-MIR172o, mdm-MIR319a, mdm-MIR319b, mdm-MIR390a, mdm-MIR390b, mdm-MIR390c, mdm-MIR390d, mdm-MIR390e, mdm-MIR390f, mdm-MIR396a, mdm-MIR396b, mdm-MIR396c, mdm-MIR396d, mdm-MIR396e, mdm-MIR396f, mdm-MIR396g, mdm-MIR399a, mdm-MIR399b, mdm-MIR399c, mdm-MIR399d, mdm-MIR399e, mdm-MIR399f, mdm-MIR399g, mdm-MIR399h, mdm-MIR399i, mdm-MIR399j, mdm-MIR2111a, mdm-MIR2111b, mdm-MIR3627a, mdm-MIR3627b, mdm-MIR3627c, mdm-MIR535a, mdm-MIR535b, mdm-MIR535c, mdm-MIR535d, mdm-MIR828a, mdm-MIR159c, mdm-MIR319c, mdm-MIR858, mdm-MIR3627d, mdm-MIR159d, mdm-MIR159e, mdm-MIR159f, mdm-MIR399k, mdm-MIR319d, mdm-MIR319e, mdm-MIR319f, mdm-MIR319g, mdm-MIR319h, mdm-MIR172p
Up-regulation of miR828, AtTAS4 and AtTAS4-siR81(-) is correlated with that of their three direct or indirect targets (PAP1/AtMYB75, AtMYB90 and AtMYB113) under phosphate (Pi) and nitrogen deficiency conditions [74], which appears to contradict the anticipated negative role of miR828 in regulation of anthocyanin production. [score:9]
To address the possibility that some MYB gene targets were missed during degradome analysis, possibly due to inactive or low levels of target gene expression in the plant tissues analyzed, we performed target prediction analysis in over 400 putative apple MYBs and identified an additional 8, 15 and 42 MYB genes with a cleavage-favorable alignment score (≤5) for miR159, miR828 and miR858, respectively. [score:9]
The miR159 target site was found to locate in the sequence-divergent region, while the miR858 and miR828 target sites both mapped to a 55-nucleotide region in the conserved coding region upstream of the divergent region, and the two sites were separated by a 12-nucleotide fragment with the position of the miR858 target site at the 5' end and that of miR828 at the 3' end (Figure 3b). [score:7]
That miR828 and miR858 targeted substantially different numbers of MYB genes despite the adjacent location of their target sites prompted us to examine conservation profiles of their target sequences at both the amino acid and nucleotide levels (Figure 4). [score:7]
More importantly, we reveal the existence of two similar but distinct regulatory networks in apple: direct miRNA targeting of a large number of MYBs and miR828-activated and MYB-derived siRNA-cascaded targeting of 77 genes primarily outside the MYB family, which has not yet been reported in other species. [score:7]
In Arabidopsis, miR828, which indirectly targets AtMYB113 through AtTAS4-siR81(-), also directly targets AtMYB113 [65]. [score:7]
The remaining 35 targets identified were shared by miR828 and miR858, with the former targeting four MYB genes and MdTAS4 and the latter targeting up to 30 genes, including 24 coding for MYB factors, 2 coding for mate efflux proteins and 3 coding for lipases (Table 2; Table S6 in Additional file 1). [score:7]
Although the footprint of the 55-nucleotide sequence encompassing both miR828 and miR858 target sites is detected in dicot and monocot species (Figure 3b), miR828 and miR858 emerged only in dicot species [41], indicating that miR828- and miR858 -mediated regulation of MYB genes is a feature of dicot species, consistent with our finding that miR828 and miR858 target a large number of MYBs in both apple and Arabidopsis (Figure 3a). [score:6]
miR828 was specifically expressed in flower while miR858 accumulated in all tissues tested, but was found to be most abundant in mature fruit (Figure 3c), suggesting that miR828 and miR858 differentially regulated their co -targeted MYBs in different tissues. [score:6]
The finding that miR828 and miR858 co -targeted a group of MYB genes prompted us to examine whether they were co-expressed or differentially regulated among apple tissues. [score:6]
However, a few of the known miRNAs, including miR319 and miR396, were found to target additional genes in apple that have not been previously reported, while others like miR828 and miR858 target an unexpectedly large number of MYB genes. [score:5]
Consistent with this prediction, miR828 and miR858 target sites, which overlap the conserved R3 region, are found in more MYBs than the miR159 target site located in the divergent region (Figure 3a). [score:5]
Interestingly, the elevated expression of PAP1/AtMYB75 (and possibly AtMYB90 and AtMYB113) induces miR828 and AtTAS4 expression, presumably through binding of these MYBs to the 5' cis-elements in MIR828 and AtTAS4 promoter regions [74]. [score:5]
Finally, we found that 10 of the 19 miR828 -targeted MYBs undergo small interfering RNA (siRNA) biogenesis at the 3' cleaved, highly divergent transcript regions, generating over 100 sequence-distinct siRNAs that potentially target over 70 diverse genes as confirmed by degradome analysis. [score:5]
Since pairing between the miRNA seed region and corresponding target site is critical for miRNA cleavage [62], the level of sequence conservation in this region could impact miR828- and miR858 -targeted MYB populations. [score:5]
miR828 and miR858 have been shown to target MYBs in other species but their target number was very limited [36, 55]. [score:5]
Interestingly, despite the apparent flower-biased expression of miR828 (Figure 3c), distinct patterns of accumulation of phased siRNAs were observed among the ten miR828 -targeted MYBs (Figure S5 in Additional file 2). [score:5]
All the apple MYB targets for miR828, miR858, and miR159 were predicted by Targetfinder 1.6 with the alignment score no more than 5. Amino acid sequences of 126 R2R3 and 5 R1R2R3 MYB factors in Arabidopsis were retrieved from TAIR [82]and the phylogenetic tree was inferred using the neighbor-joining method and 1,000 bootstraps with putative full-length sequences using CLUSTAL X2 [81]. [score:5]
Conceivably, the miR828-activated siRNA biogenesis in seven of the ten targeted MYBs that relate to anthocyanin accumulation in apple would reinforce this feedback regulation to ensure proper color appearance in a specific tissue or apple fruit during development. [score:5]
We also found that miR858 shared 11 targets with miR828 and two with miR159 (Figure 3a; Table S7 in Additional file 1), but no common target was identified for miR828 and miR159. [score:5]
Correspondingly, the miR858 target site was found to be more conserved than the miR828 target site at the nucleotide level in both apple and Arabidopsis (Figure 4e; Figure S3b in Additional file 2). [score:5]
Of the 18 amino acid residues, the first seven (1 to 7) encoded by the 21-nucleotide miR858 target site were located in the highly conserved region covering three amino acid residues upstream and four amino acid residues at the 5' end of H3 while most of the last seven (12 to 18) encoded by the miR828 target site were located in the much less conserved region downstream of H3 (Figure 4c, d). [score:5]
This difference was particularly pronounced in a region (positions 10 to 20 in the miR858 target site, and 44 to 54 in the miR828 target site) that specifically pairs with the miRNA seed region (positions 2 to 12) (Figure 4e; Figure S3b in Additional file 2). [score:5]
For example, leaf- and root-biased expression was observed for miR535, while flower-biased expression was apparent for miR828 (Figure 1b). [score:5]
With direct searching against small sequencing libraries, we were able to map a large number of sRNA reads to the coding regions of ten miR828 -targeted MYBs. [score:4]
The detection of differential expression of miR828 and miR858 among various tissues appears to support their different regulatory roles (Figure 3c). [score:4]
Importantly, we found that miR159, miR828 and miR858 can collectively target up to 81 MYB genes potentially involved in diverse aspects of plant growth and development. [score:4]
Finding an unusually large number of MYB targets for miR828 and miR858 suggests that they gained more diverse and broad regulatory roles in apple. [score:4]
Nine of the ten MYBs co -targeted by miR828 and miR858 cluster together within subgroup 5, which is involved in the regulation of proanthocyanidin biosynthesis (Figure 3d). [score:4]
Notably, most of the miR828 -targeted MYBs are linked with primary and secondary metabolism related to anthocyanin production and color development. [score:4]
The latter possibility is favored by the fact that 10 out of 11 MYBs co -targeted by miR828 and miR858 are related to regulation of anthocyanin biosynthesis. [score:4]
In Arabidopsis, the transcript from a trans-acting siRNA (TAS) gene is first cleaved by one of three specialized miRNAs (miR173, miR390 and miR828), and then either the 3'-cleaved (in the case of miRNA828, miR173) or the 5'-cleaved transcript fragments (in the case of miR390) are converted into double-stranded RNAs by RDR6 and subsequently diced into phased 21-nucleotide siRNAs by DCL4 to generate multiple but distinct tasiRNA species, some of which are found to further guide sequence-specific cleavage of their targeted gene transcripts through the RISC [5, 17- 20]. [score:3]
Analysis of siRNA abundance in four libraries showed that MdTAS4-derived tasiRNAs primarily accumulated in flower tissues (Figure S4E in Additional file 2), which is in agreement with the flower-biased expression of miR828 in apple (Figure 3c). [score:3]
These MYBs share similar genomic organization with the location of the miR828 target site in the third exon just before the divergent region where siRNA biogenesis occurred (Figure 5f). [score:3]
Both miR390 and miR828 were identified in apple (Figure 1a, b), and showed highest expression specifically in flower as detected by RNA blot and RNA sequencing methods (Figures 1a, b and 3C). [score:3]
The dual cleavage by miR858 and miR828 was confirmed in one of the targeted MYBs (MDP0000124555) by RNA ligation -mediated 5' rapid amplification of cDNA ends (RLM-5'-RACE) analysis (Figure 3b). [score:3]
In Arabidopsis, miR159, miR828 and miR858 were either predicted or confirmed to target at least 13 MYB genes [56, 57]. [score:3]
Figure S5: distribution analysis of siRNAs derived from the ten miR828 -targeted MYB genes. [score:3]
Based on alignment scores ≤5, 66 and 19 apple MYBs were identified to be targeted by miR858 and miR828, respectively (Figure 3a). [score:3]
Table S7: MYB genes targeted by miR828, mi858, and miR159. [score:3]
Sequencing data showed that abundant 21-nucleotide sRNAs were produced along the 3' cleaved MdTAS4 transcript, and most of those sRNAs belonged to the first (miR828 target site) and second register while some of them fell into the 12th register (Figure S4E in Additional file 2). [score:3]
miR828-activated, MYB transcript-derived siRNAs and their gene targets. [score:3]
The 19 miR828 -targeted MYBs were related to three subgroups: S6, S7 and S15 (Figure 3d). [score:3]
These results imply that the targeting capacity of miR858 and miR828 in apple and Arabidopsis might be even broader than those reported in Figure 3a, especially for miR858. [score:3]
miR828-activated, MYB transcript-derived siRNAs and their gene targetsThe possibility that miR828-cleaved TAS4 RNA fragments could be channeled into tasiRNA biogenesis [30, 65] led us to examine whether all miR828-cleaved MYB transcripts are also subjected to tasiRNA biogenesis. [score:3]
The co -targeting sequence of miR828 and miR858 is located in the region encoding the conserved R3 repeat domain of MYB proteins. [score:3]
Similarly, the miR858 target site, which overlaps the more highly conserved 5' end of the H3 domain, is conserved in more MYBs than the miR828 site, which overlaps the less conserved 3' end of the H3 domain (Figure 4c-4e). [score:3]
One of the interesting findings in this study is that miR828 potentially targets up to 19 MYBs in apple, 10 of which are subjected to siRNA biogenesis, with production of over 100 diverse siRNA species from the diverged region of MYBs (Figure 5f). [score:3]
Pairing of miR828 and miR858 with their target sites in a representative MYB transcript is illustrated below. [score:3]
One interesting feature of the apple miR828- TAS4 pathway is that its derived tasiRNA, MdTAS4-siR81(-), targets an additional gene. [score:3]
Intriguingly, miR858 was found to co-target 11 MYBs with miR828 and two MYBs with miR159 (Figure 3a), raising the question of whether the convergence of two miRNAs upon the same MYB genes is an evolutionary coincidence or conveys some biological significance. [score:3]
Figure 4 The co -targeting sequence of miR858 and miR828 is located in the region encoding the R3 repeat domain of MYB proteins. [score:3]
Strikingly, this 55-nucleotide fragment encompassing the miR858 and miR828 targeted sequences and 12-nucleotide spacer was found to be highly conserved across a wide range of dicots and monocots (Figure 3b). [score:3]
miR828 -targeted MYBs capable of producing secondary siRNAs are marked with a star, and MYBs whose cleavage was confirmed by degradome analysis are marked with filled circles. [score:3]
We found that the18 amino acid polypeptide encoded by the 55-nucleotide sequence that bears both miR828 and miR858 target sites was located in the conserved R3 DNA binding domain of MYB factors (Figure 4a). [score:3]
Figures 1b and 3c show that miR828 and miR858 exhibit a distinct expression pattern that was generally corroborated by boths and RNA sequencing. [score:3]
Figure S4: T-plots for targets of miR828, miR858 and tasiARF. [score:3]
Apple TAS gene families with unique features and target specificityIn Arabidopsis, four TAS families targeted by three miRNAs, including miR173, miR390 and miR828, have been characterized [5, 17- 20, 30, 63]. [score:3]
miR828 and miR858 may either redundantly reinforce each other's silencing function or differentially regulate anthocyanin accumulation in various apple tissues. [score:2]
Unique miR828-activated, siRNA-cascaded gene regulatory network and its potential biological function. [score:2]
Thus, a total of nine MYBs for miR159, 19 for miR828 and 66 for miR858 were found, bringing the total number of MYBs potentially regulated by these miRNAs to 81 (Figure 3a; Table S7 in Additional file 1). [score:2]
Thus, the roles of miR858 -mediated regulation of MYBs in apple are predicted to be much broader than those for either miR828 or miR159. [score:2]
Figure 3Complex MYB regulatory network mediated by miR159, miR828, and miR858. [score:2]
In contrast, 211 of the 251 MYBs showed a cleavage-unfavorable alignment score (> 7) with miR828 while only a very small portion of them had a cleavage-favorable or less cleavage-favorable alignment score (≤7) (Figure 4b, top). [score:1]
We found that while blotting results for some miRNAs - miR828, miR858, miR390 (Figure 3c) and miR4376 (Figure 1c) - were reflective of the relative abundances of sequenced RNAs from these four tissues, many others displayed varying degrees of divergence between the two analyses. [score:1]
The miR390- TAS3 pathway is highly conserved in the plant kingdom [20], and the miR828- TAS4 pathway is wi dely represented in dicot species [65], but no miR173- TAS1/ TAS2 pathway has been found in other species besides Arabidopsis. [score:1]
The miR828 cleavage of MdTAS4 transcripts and generation of the conserved MdTAS4-siR81(-) are marked on the transcript. [score:1]
To date, only four TAS families (AtTAS1-4) and three miRNAs (miR173, miR828, and miR390) that target TAS transcripts and trigger tasiRNA production have been reported and well characterized in Arabidopsis [5, 18- 20, 30]. [score:1]
In this study, we showed that apple conserved the miR390- TAS3 and miR828- TAS4 pathways with expanded features. [score:1]
In Arabidopsis, four TAS families targeted by three miRNAs, including miR173, miR390 and miR828, have been characterized [5, 17- 20, 30, 63]. [score:1]
The possibility that miR828-cleaved TAS4 RNA fragments could be channeled into tasiRNA biogenesis [30, 65] led us to examine whether all miR828-cleaved MYB transcripts are also subjected to tasiRNA biogenesis. [score:1]
A TAS4 homolog, MdTAS4, was found in apple (Figure 5e), and degradome analysis showed that miR828 cleaved MdTAS4 (Figure S4E in Additional file 2). [score:1]
Further analysis showed that the generated siRNAs were in phase with the miR828 cleavage site, and the siRNA generation pattern varied among the ten MYBs (Figure S5 in Additional file 2). [score:1]
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[+] score: 55
Other miRNAs from this paper: mdm-MIR482a, mdm-MIR156a, mdm-MIR156b, mdm-MIR156c, mdm-MIR156d, mdm-MIR156e, mdm-MIR156f, mdm-MIR156g, mdm-MIR156h, mdm-MIR156i, mdm-MIR156j, mdm-MIR156k, mdm-MIR156l, mdm-MIR156m, mdm-MIR156n, mdm-MIR156o, mdm-MIR156p, mdm-MIR156q, mdm-MIR156r, mdm-MIR156s, mdm-MIR156t, mdm-MIR156u, mdm-MIR156v, mdm-MIR156w, mdm-MIR156x, mdm-MIR156y, mdm-MIR156z, mdm-MIR156aa, mdm-MIR156ab, mdm-MIR156ac, mdm-MIR156ad, mdm-MIR156ae, mdm-MIR160a, mdm-MIR160b, mdm-MIR160c, mdm-MIR160d, mdm-MIR160e, mdm-MIR164a, mdm-MIR164b, mdm-MIR164c, mdm-MIR164d, mdm-MIR164e, mdm-MIR164f, mdm-MIR167a, mdm-MIR167b, mdm-MIR167c, mdm-MIR167d, mdm-MIR167e, mdm-MIR167f, mdm-MIR167g, mdm-MIR167h, mdm-MIR167i, mdm-MIR167j, mdm-MIR168a, mdm-MIR169a, mdm-MIR169b, mdm-MIR169c, mdm-MIR169d, mdm-MIR171a, mdm-MIR171b, mdm-MIR171c, mdm-MIR171d, mdm-MIR171e, mdm-MIR171f, mdm-MIR171g, mdm-MIR171h, mdm-MIR171i, mdm-MIR171j, mdm-MIR171k, mdm-MIR171l, mdm-MIR171m, mdm-MIR171n, mdm-MIR172a, mdm-MIR172b, mdm-MIR172c, mdm-MIR172d, mdm-MIR172e, mdm-MIR172f, mdm-MIR172g, mdm-MIR172h, mdm-MIR172i, mdm-MIR172j, mdm-MIR172k, mdm-MIR172l, mdm-MIR172m, mdm-MIR172n, mdm-MIR172o, mdm-MIR393a, mdm-MIR393b, mdm-MIR393c, mdm-MIR395a, mdm-MIR395b, mdm-MIR395c, mdm-MIR395d, mdm-MIR395e, mdm-MIR395f, mdm-MIR395g, mdm-MIR395h, mdm-MIR395i, mdm-MIR396a, mdm-MIR396b, mdm-MIR396c, mdm-MIR396d, mdm-MIR396e, mdm-MIR396f, mdm-MIR396g, mdm-MIR397a, mdm-MIR397b, mdm-MIR398a, mdm-MIR398b, mdm-MIR398c, mdm-MIR399a, mdm-MIR399d, mdm-MIR399i, mdm-MIR408a, mdm-MIR3627a, mdm-MIR3627b, mdm-MIR3627c, mdm-MIR391, mdm-MIR477b, mdm-MIR477a, mdm-MIR482b, mdm-MIR482c, mdm-MIR535a, mdm-MIR535b, mdm-MIR535c, mdm-MIR535d, mdm-MIR827, mdm-MIR828a, mdm-MIR408b, mdm-MIR408c, mdm-MIR408d, mdm-MIR482d, mdm-MIR7121a, mdm-MIR7121b, mdm-MIR7121c, mdm-MIR7121d, mdm-MIR7121e, mdm-MIR7121f, mdm-MIR7121g, mdm-MIR7121h, mdm-MIR5225c, mdm-MIR7124a, mdm-MIR5225a, mdm-MIR5225b, mdm-MIR7125, mdm-MIR393d, mdm-MIR393e, mdm-MIR393f, mdm-MIR7127a, mdm-MIR7127b, mdm-MIR171o, mdm-MIR169e, mdm-MIR169f, mdm-MIR858, mdm-MIR3627d, mdm-MIR395j, mdm-MIR169g, mdm-MIR169h, mdm-MIR169i, mdm-MIR169j, mdm-MIR171p, mdm-MIR393g, mdm-MIR393h, mdm-MIR395k, mdm-MIR171q, mdm-MIR169k, mdm-MIR169l, mdm-MIR169m, mdm-MIR169n, mdm-MIR172p, mdm-MIR395l, mdm-MIR169o
The expression profiles of MdSPL9 (MDP0000297978), MdbHLH (MDP0000225680), MdMYB9 (MDP0000210851), and MdANR2 (MDP0000320264) target genes regulated by mdm-miR156, mdm-miR828, mdm-miR858 and miR5072 were analyzed, respectively. [score:6]
It has been reported that miR828 and miR858 could directly or indirectly control anthocyanin biosynthesis in apple, and differentially expressed miR156 can positively regulate anthocyanin biosynthesis by the SPL transcription factor in Arabidopsis thaliana (Gou et al., 2011; Xia et al., 2012). [score:6]
MdMYB transcription factors and anthocyanin regulatory C1 protein-like were found to serve as the target genes of miR828 and miR858. [score:4]
In addition, miRNA828 can regulate anthocyanin biosynthesis through its target gene AtTAS4-siR81(-). [score:4]
” MdTAS4-siR81(-), derived from the miR828-TAS4 pathway, has three predictable MYB target genes. [score:3]
Among them, the expression of MdbHLH gene was a perfect inverse to that of mdm-miR828 in both cultivars. [score:3]
Therefore, MdbHLH transcription factor was one target gene of mdm-miR828. [score:3]
The expression levels of “Starkrimson” mdm-miR828 in the treatment group were only slight increased to their highest level at 4 days, and then decreased at 6 days. [score:3]
The expression levels of four known miRNAs (mdm-miR156, mdm-miR828, mdm-miR858, and miR5072) and their target genes were investigated by using qRT-PCR (Figures 7, 8). [score:3]
Previous study shows that miR828 is specifically expressed in apple flowers, but miR858 accumulates most abundantly in mature apple fruit (Xia et al., 2012), in agreement with our results that the normalized reads of miR858 were 120-fold higher than that of miR828. [score:3]
In our study, we found several target genes of miR828 were related to anthocyanin biosynthesis in apple peel after debagging. [score:3]
” MdTAS4-siR81(-), derived from the miR828-TAS4 pathway, has three predictable MYB target genes. [score:3]
The expression levels of mdm-miR828 in treatment and control groups of “Granny Smith” sharply increased and reached to highest level at 2 day, then both of them dramatically decreased to undetectable level at 6 days. [score:3]
Interestingly, our results found that the expression levels of mdm-miR156, mdm-miR828 and mdm-miR858 were different when fruits were debagged. [score:3]
” It can be inferred that mdm-miR828 and MdbHLH gene could have an important influence in regulating the accumulation of anthocyanin in the two cultivars. [score:2]
Among them, mdm-miR828 and mdm-miR828might play important roles in the accumulation of anthocyanin after debagging in “Granny Smith” and “Starkrimson” apple cultivars. [score:1]
In the control group, the transcription level of mdm-miR828 gradually increased from 0 h to 6 days. [score:1]
For example, seven known miRNAs (miR160, miR164, miR395, miR477, miR5225, miR7125, and miR828) were present in all the three groups. [score:1]
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3
[+] score: 9
Other miRNAs from this paper: mdm-MIR482a, mdm-MIR156a, mdm-MIR156b, mdm-MIR156c, mdm-MIR156d, mdm-MIR156e, mdm-MIR156f, mdm-MIR156g, mdm-MIR156h, mdm-MIR156i, mdm-MIR156j, mdm-MIR156k, mdm-MIR156l, mdm-MIR156m, mdm-MIR156n, mdm-MIR156o, mdm-MIR156p, mdm-MIR156q, mdm-MIR156r, mdm-MIR156s, mdm-MIR156t, mdm-MIR156u, mdm-MIR156v, mdm-MIR156w, mdm-MIR156x, mdm-MIR156y, mdm-MIR156z, mdm-MIR156aa, mdm-MIR156ab, mdm-MIR156ac, mdm-MIR156ad, mdm-MIR156ae, mdm-MIR159a, mdm-MIR159b, mdm-MIR160a, mdm-MIR160b, mdm-MIR160c, mdm-MIR160d, mdm-MIR160e, mdm-MIR164a, mdm-MIR164b, mdm-MIR164c, mdm-MIR164d, mdm-MIR164e, mdm-MIR164f, mdm-MIR166a, mdm-MIR166b, mdm-MIR166c, mdm-MIR166d, mdm-MIR166e, mdm-MIR166f, mdm-MIR166g, mdm-MIR166h, mdm-MIR166i, mdm-MIR167a, mdm-MIR167b, mdm-MIR167c, mdm-MIR167d, mdm-MIR167e, mdm-MIR167f, mdm-MIR167g, mdm-MIR167h, mdm-MIR167i, mdm-MIR167j, mdm-MIR168a, mdm-MIR168b, mdm-MIR169a, mdm-MIR169b, mdm-MIR169c, mdm-MIR169d, mdm-MIR171a, mdm-MIR171b, mdm-MIR171c, mdm-MIR171d, mdm-MIR171e, mdm-MIR171f, mdm-MIR171g, mdm-MIR171h, mdm-MIR171i, mdm-MIR171j, mdm-MIR171k, mdm-MIR171l, mdm-MIR171m, mdm-MIR171n, mdm-MIR172a, mdm-MIR172b, mdm-MIR172c, mdm-MIR172d, mdm-MIR172e, mdm-MIR172f, mdm-MIR172g, mdm-MIR172h, mdm-MIR172i, mdm-MIR172j, mdm-MIR172k, mdm-MIR172l, mdm-MIR172m, mdm-MIR172n, mdm-MIR172o, mdm-MIR393a, mdm-MIR393b, mdm-MIR393c, mdm-MIR395a, mdm-MIR395b, mdm-MIR395c, mdm-MIR395d, mdm-MIR395e, mdm-MIR395f, mdm-MIR395g, mdm-MIR395h, mdm-MIR395i, mdm-MIR396a, mdm-MIR396b, mdm-MIR396c, mdm-MIR396d, mdm-MIR396e, mdm-MIR396f, mdm-MIR396g, mdm-MIR397a, mdm-MIR397b, mdm-MIR399a, mdm-MIR399b, mdm-MIR399c, mdm-MIR399d, mdm-MIR399e, mdm-MIR399f, mdm-MIR399g, mdm-MIR399h, mdm-MIR399i, mdm-MIR399j, mdm-MIR391, mdm-MIR482b, mdm-MIR482c, mdm-MIR535a, mdm-MIR535b, mdm-MIR535c, mdm-MIR535d, mdm-MIR827, mdm-MIR828a, mdm-MIR482d, mdm-MIR7123a, mdm-MIR7123b, mdm-MIR5225c, mdm-MIR159c, mdm-MIR7124a, mdm-MIR7124b, mdm-MIR5225a, mdm-MIR5225b, mdm-MIR7125, mdm-MIR7126, mdm-MIR393d, mdm-MIR393e, mdm-MIR393f, mdm-MIR171o, mdm-MIR169e, mdm-MIR169f, mdm-MIR7128, mdm-MIR858, mdm-MIR1511, mdm-MIR159d, mdm-MIR159e, mdm-MIR159f, mdm-MIR166j, mdm-MIR399k, mdm-MIR395j, mdm-MIR169g, mdm-MIR169h, mdm-MIR169i, mdm-MIR169j, mdm-MIR171p, mdm-MIR393g, mdm-MIR393h, mdm-MIR395k, mdm-MIR171q, mdm-MIR169k, mdm-MIR169l, mdm-MIR169m, mdm-MIR169n, mdm-MIR172p, mdm-MIR395l, mdm-MIR169o
miRNA828 and miRNA858 target the MYB family at the R3 domian (Xia et al., 2012; Figure 6B). [score:3]
The potential targets of miR858, miR828, and miR156 participate in the fatty acid biosynthetic process. [score:3]
The potential targets of miR159, miR166, miR167, miR171, miR172, miR393, miR858, and miR828 are involved in cell growth. [score:3]
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4
[+] score: 4
Other miRNAs from this paper: ppe-MIR171f, ppe-MIR394a, ppe-MIR828, ppe-MIR171h, ppe-MIR171a, ppe-MIR171e, ppe-MIR171g, ppe-MIR171b, ppe-MIR171c, mdm-MIR156a, mdm-MIR156b, mdm-MIR156c, mdm-MIR156d, mdm-MIR156e, mdm-MIR156f, mdm-MIR156g, mdm-MIR156h, mdm-MIR156i, mdm-MIR156j, mdm-MIR156k, mdm-MIR156l, mdm-MIR156m, mdm-MIR156n, mdm-MIR156o, mdm-MIR156p, mdm-MIR156q, mdm-MIR156r, mdm-MIR156s, mdm-MIR156t, mdm-MIR156u, mdm-MIR156v, mdm-MIR156w, mdm-MIR156x, mdm-MIR156y, mdm-MIR156z, mdm-MIR156aa, mdm-MIR156ab, mdm-MIR156ac, mdm-MIR156ad, mdm-MIR156ae, mdm-MIR159a, mdm-MIR159b, mdm-MIR160a, mdm-MIR160b, mdm-MIR160c, mdm-MIR160d, mdm-MIR160e, mdm-MIR164a, mdm-MIR164b, mdm-MIR164c, mdm-MIR164d, mdm-MIR164e, mdm-MIR164f, mdm-MIR166i, mdm-MIR167a, mdm-MIR167b, mdm-MIR167c, mdm-MIR167d, mdm-MIR167e, mdm-MIR167f, mdm-MIR167g, mdm-MIR167h, mdm-MIR167i, mdm-MIR167j, mdm-MIR171a, mdm-MIR171b, mdm-MIR171c, mdm-MIR171d, mdm-MIR171e, mdm-MIR171f, mdm-MIR171g, mdm-MIR171h, mdm-MIR171i, mdm-MIR171j, mdm-MIR171k, mdm-MIR171l, mdm-MIR171m, mdm-MIR171n, mdm-MIR172a, mdm-MIR172b, mdm-MIR172c, mdm-MIR172d, mdm-MIR172e, mdm-MIR172f, mdm-MIR172g, mdm-MIR172h, mdm-MIR172i, mdm-MIR172j, mdm-MIR172k, mdm-MIR172l, mdm-MIR172m, mdm-MIR172n, mdm-MIR172o, mdm-MIR394a, mdm-MIR394b, mdm-MIR396e, mdm-MIR828a, mdm-MIR159c, mdm-MIR171o, mdm-MIR858, ppe-MIR156a, ppe-MIR156b, ppe-MIR156c, ppe-MIR156d, ppe-MIR156e, ppe-MIR156f, ppe-MIR156g, ppe-MIR156h, ppe-MIR156i, ppe-MIR159, ppe-MIR160a, ppe-MIR160b, ppe-MIR164a, ppe-MIR164b, ppe-MIR164c, ppe-MIR164d, ppe-MIR167a, ppe-MIR167b, ppe-MIR167c, ppe-MIR167d, ppe-MIR171d, ppe-MIR172a, ppe-MIR172b, ppe-MIR172c, ppe-MIR172d, ppe-MIR394b, ppe-MIR858, mdm-MIR159d, mdm-MIR159e, mdm-MIR159f, mdm-MIR171p, mdm-MIR171q, mdm-MIR172p
In addition, miR828, and miR858, which are also involved in R2R3-MYB regulation[72] was predicted target MYB genes in Rosa (Additional file 2). [score:4]
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5
[+] score: 2
They also discovered myeloblastosis (MYB) genes from which phasiRNAs were generated after cleavage by miR828. [score:1]
No members were detected for the miR828, miR2111 and miR7128 families. [score:1]
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