12 publications mentioning bta-mir-133c

Open access articles that are associated with the species Bos taurus and mention the gene name mir-133c. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1

Although the bovine-specific target genes of miRNA-206, miRNA-1, miRNA-133, miRn12, and miRn17 are not known, their consistent expression pattern and high conservation indicate that they are also likely to play roles in the development of bovine muscle tissues.

Comparison of miRNA expression profiles among tissues revealed that miR-2284x in liver, and miRNA-206, miRNA-1, miRNA-133, miRn12, and miRn17 in muscle-related tissue or organs (skeletal muscle, heart, intestines) were highly expressed (Figure 3).

Based on stem-loop qPCR, 25 high-read miRNAs were detected, and the results showed that bta-miRNA-206, miRNA-1, miRNA-133, miRNAn12, and miRNAn17 were highly expressed in muscle-related tissue or organs, suggesting that these miRNAs may play a role in the development of bovine muscle tissues.

Previous studies in vitro have shown that miR-1, miR-133, and miR-206 can target multiple muscle-development-related genes.

The results showed that expression of bta-miRNA-133 and miRn12 was increased in the muscle tissues from day 90 bovine embryos to 2-year-olds, respectively.

For example, miR-1 and miR-133 have distinct roles in modulating skeletal muscle proliferation and differentiation in cultured myoblasts in vitro and in Xenopus laevis embryos in vivo.

In contrast, miR-133 enhances myoblast proliferation by repressing SRF [44].

MiR-206, miR-1, and miR-133 are muscle specific miRNAs [9].

In contrast, miR-133 enhances myoblast proliferation by repressing serum response factor (SRF) [8].

2

Moreover, forced expression of miR-133 decreased GLUT4 expression and reduced insulin -mediated glucose uptake in cardiomyocytes [52].

miR-1 and miR-206 were upregulated during satellite cell differentiation and promoted myogenesis [28, 33], whereas miR-133 was involved primarily in the promotion of proliferation [9].

Based on abundance levels, miR-206 and miR-1 were considered to have a greater role in MDSC differentiation than miR-133 or their targets could be more abundant.

To date, several miRNAs have been reported to regulate lipid metabolism, including miR-122, miR-33a, miR-133, miR-335, miR-125a, and miR-34a [48].

For example, miR-1 and miR-206 could promote the differentiation of myoblasts, whereas miR-133 could promote cell proliferation [8– 10].

In addition, both miR-206 and miR-1 promoted differentiation [9], which suggested that these two miRNAs might have a greater effect than miR-133 in muscle satellite cell differentiation [35].

Interestingly, miR-133 was detected at low levels in MDSC-D1, but higher in MDSC-D3.

3

MiR-133 and miR-1 are preferentially expressed in cardiac and skeletal muscles in Xenopus laevis [39] both have opposing effects, with miR-1 being rather pro-apoptotic [38].

Although rmi-miR-1 is the most abundantly expressed miRNA in cattle tick larvae (Figure 3B), we found eight other miRNAs, including rmi-miR-133, rmi-miR-87, rmi-miR-10, and rmi-miR-252, that had a higher fold-change ratio in miRNA transcript levels as compared to that in eggs suggesting that these miRNAs may play a role during larval development (Table 3 and Additional file 6).

Complete list of miRNAs and statistics are shown in Additional file 9. In male ticks we found 9 miRNAs up regulated in comparison to female ticks (P < 9.62E-05) including rmi-miR-133, rmi-miR-bantam, rmi-miR-279 and rmi-miR-310/miR-92 (Table 5 and Additional file 9).

It is intriguing to observe the up regulation of two known anti-apoptotic miRNAs, rmi-miR-bantam and rmi-miR-133 in adult males [37, 38].

Complete list of miRNAs and statistics are shown in Additional file 9. In male ticks we found 9 miRNAs up regulated in comparison to female ticks (P < 9.62E-05) including rmi-miR-133, rmi-miR-bantam, rmi-miR-279 and rmi-miR-310/miR-92 (Table 5 and Additional file 9).

4

Comparison of miRNA expression profiles among tissues revealed that miR-154c in fat, and miRNA-1, miRNA-133 and miRNA-206 in muscle-related tissue or organs (skeletal muscle, heart) were specially expressed (Figure 5).

Previous studies have shown that miR-1, miR-133, and miR-206 can target multiple muscle development related genes.

MiR-1 and miR-133, as well as miR-206, are all muscle specific miRNAs [8].

MiR-1 and miR-133 have distinct roles in modulating skeletal muscle proliferation and differentiation in cultured myoblasts in vitro and in Xenopus laevis embryos in vivo [9].

In contrast, miR-133 enhances myoblast proliferation by repressing SRF [42].

5

Upregulation of both miR-133 and myogenin under IGF-1 influence has also been described [34].

MiR-133, another myomiR, has been confirmed to increase myoblast proliferation and regulate differentiation by targeting SRF, MAML1, nPTB, and UCP2 proteins [10, 32].

Cell culture experiments have shown that miR-1 and miR-206 promote muscle cell differentiation, whereas miR-133 enhances cell proliferation.

The combined action of miR-133 and myomiRs (miR-1 and -206) induces MYOD1, PAX7, and myogenin causing myoblast differentiation [33].

It is plausible that in HER/LIM cells, the differentiation progression is accelerated via similar mechanisms involving miR-1, miR-133, miR-206, and myogenin, resulting possibly in enhanced myotube formation observed in the primary cultures of the skeletal muscle with a HER/LIM origin (Fig. 1).

6

Duran et al. (2015) analyzed the impact of the miRNA-target interactions of miR-1/ hdac4, miR-133-a/b/ srf, miR-206/ pax7, and miR-499/ sox6 in fast- and slow-twitch skeletal muscles during growth.

Salem et al. (2010) showed that miR-133, which is known to be enriched in mammalian muscle (Shingara et al., 2005; Ason et al., 2006; Chen et al., 2006), is also highly expressed in trout skeletal muscle and therefore is of interest in animal breeding.

The expression pattern of 12 miRNAs, including mir-1, mir-133 and mir-206, was validated by real time PCR.

For instance, the role ofmiR-1, miR-206, and miR-133 during myoblast proliferation and differentiation is recognized to interfere in the hypertrophic growth of skeletal muscle.

The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation.

7

For instance, linc-MD1 is a muscle-specific intergenic lncRNA that acts as a sponge for miR-133 and miR-135, preventing their suppression of MAML1 and MEF2C and activating muscle-specific gene expression [6].

8

Accordingly, the three miRNAs (Fig.   5a) were expressed predominantly in liver (miR-122, 88-fold higher than in any other tissue), muscle/heart (miR-133, 254-fold higher) and intestine (miR-215, 150-fold higher).

9

Differences in epigenetics between breeds[55] Insulin-like growth factor-1 receptor is regulated by microRNA-133 during skeletal myogenesis.

10

Current data on the role of miRNAs in myogenesis has been obtained largely from studies on muscle-specific miR-1, miR-133 and miR-206.

11

miR-1 and miR-133 have distinct roles in modulating skeletal muscle proliferation and differentiation in cultured myoblast in vitro and in Xenopus laevis embryos in vivo[9].

12

Chen J. -F. Man del E. M. Thomson J. M. Wu Q. Callis T. E. Hammond S. M. Conlon F. L. Wang D. Z. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation Nat.