Accession
MI0000098
Symbol
HGNC:
MIR96
Description
Homo sapiens
hsa-mir-96 precursor miRNA mir-96
Gene
family?
family?
RF00669;
mir-96
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR96 is a microRNA implicated in the pathogenesis of progressive hearing loss, where understanding the various pathogenic mechanisms associated with MIR96 mutations is essential for the development of personalized therapies for affected individuals [PMC3259013]. However, research into MIR96 has been hindered by inadequate sequencing coverage, which poses a challenge in fully elucidating its role in hearing impairment [PMC8738750].
Literature search
193 open access papers mention hsa-mir-96
(1229 sentences)
(1229 sentences)
Sequence
77874
reads,
304
reads per million, 122 experiments
uggccgauUUUGGCACUAGCACAUUUUUGCUugugucucuccgcucugagcAAUCAUGUGCAGUGCCAAUAUGggaaa
...((.((.((((((((.((((((..(((((((((......)))...))))))..)))))))))))))).)).))...
...((.((.((((((((.((((((..(((((((((......)))...))))))..)))))))))))))).)).))...
Structure
ugg g U A UU --- uc cc au UUGGCACU GCACAU UUGCUu gug u || || |||||||| |||||| |||||| ||| gg UA AACCGUGA CGUGUA AAcgag cgc c aaa G U - CU ucu cu
Annotation confidence
Medium
Do you think this miRNA is real?
Comments
This sequence is localised to chromosome 7 and was named mir-96-7 in reference [1]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].
Genome context
chr7: 129774692-129774769 [-]
Clustered miRNAs
2 other miRNAs are < 10 kb from hsa-mir-96
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Disease association
hsa-mir-96 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-96-5p
| Accession | MIMAT0000095 |
| Description | Homo sapiens hsa-miR-96-5p mature miRNA |
| Sequence | 9 - UUUGGCACUAGCACAUUUUUGCU - 31 |
| Evidence |
experimental
cloned [1-3] |
| Database links |
|
| Predicted targets |
|
Mature hsa-miR-96-3p
| Accession | MIMAT0004510 |
| Description | Homo sapiens hsa-miR-96-3p mature miRNA |
| Sequence | 52 - AAUCAUGUGCAGUGCCAAUAUG - 73 |
| Evidence |
experimental
cloned [2] |
| Database links |
|
| Predicted targets |
|
References
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