Stem-loop mmu-mir-155

Accession

MI0000177

Symbol

MGI: Mir155

Description

Mus musculus mmu-mir-155 precursor miRNA mir-155

Gene
family

RF00731; mir-155

Literature search

508 open access papers mention mmu-mir-155
(8083 sentences)

Sequence

115386 reads, 439 reads per million, 101 experiments

cugUUAAUGCUAAUUGUGAUAGGGGUuuuggccucugacugaCUCCUACCUGUUAGCAUUAACag
((((((((((((((.(.(.((((((((..(........).)))))))))).))))))))))))))

Structure

              U U A        uu gcc 
cugUUAAUGCUAAU G G UAGGGGUu  g   u
|||||||||||||| | | ||||||||  |    
gaCAAUUACGAUUG C C AUCCUCag  c   c
              U - -        -u agu 

Annotation confidence High

Comments

Mouse mir-155 resides in the non-coding BIC transcript (EMBL:AY096003), located on chromosome 16 [2]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context

chr16: 84714140-84714204 [+]

Mature mmu-miR-155-5p

• Accession: MIMAT0000165
• Description: Mus musculus mmu-miR-155-5p mature miRNA
• Sequence: 4 - UUAAUGCUAAUUGUGAUAGGGGU - 26
• Evidence: experimental ; cloned [1,3], Illumina [5]

Mature mmu-miR-155-3p

• Accession: MIMAT0016993
• Description: Mus musculus mmu-miR-155-3p mature miRNA
• Sequence: 43 - CUCCUACCUGUUAGCAUUAAC - 63
• Evidence: experimental ; 454 [4], Illumina [5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739


3. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


4. PubMed ID: 15634332
   New human and mouse microRNA genes found by homology search
   "Weber MJ"
   "FEBS J (2005) 272:59-73


5. PubMed ID: 20668074
   Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68
   "Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H"
   "J Virol (2010) 84:10266-10275