miRBase entry: ath-MIR159a

Stem-loop ath-MIR159a

Arabidopsis thaliana ath-MIR159a precursor miRNA
Gene family
MIPF0000010; MIR159

Literature search
52 open access papers mention ath-MIR159a
(497 sentences)



            aa        cau    -u    ------       aga      g  a  c    g uc     -    cu       guaa 
guagagcuccuu  aguucaaa   gagu  gagc      aggguaa   aaagcu cu ag uaug a  ccaua agcc  aauccuu    a
||||||||||||  ||||||||   ||||  ||||      |||||||   |||||| || || |||| |  ||||| ||||  |||||||    g
cAUCUCGAGGGA  UUAGGUUU   cuca  uucg      ucccguu   uuucga ga uc auac u  gguau uugg  uuaggaa    u
            AG        cuu    uu    guaauu       caa      g  c  u    g ua     a    -u       aaaa 

Annotation confidence Not enough data
Do you think this miRNA is real?
MIR159a was identified independently by Reinhart et al. [1] and Mette et al. [2]. The latter group referred to this sequence by the internal identifier MIR40a. This sequence is not related to C. elegans miR-40. MIR159a is thought to target mRNAs coding for MYB proteins which are known to bind to the promoter of the floral meristem identity gene LEAFY [3].

Genome context
chr1: 27713233-27713416 [-]

Database links

Mature ath-miR159a

Accession MIMAT0000177
Description Arabidopsis thaliana ath-miR159a mature miRNA
Evidence experimental
cloned [1,4], Northern [1], 5'RACE [4], 454 [5-6], MPSS [5], Illumina [7]


  1. PubMed ID: 12101121
    MicroRNAs in plants
    "Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP"
    "Genes Dev (2002) 16:1616-1626

  2. PubMed ID: 12202040
    Prediction of plant microRNA targets
    "Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP"
    "Cell (2002) 110:513-520

  3. PubMed ID: 16040653
    Expression of Arabidopsis MIRNA genes
    "Xie Z, Allen E, Fahlgren N, Calamar A, Givan SA, Carrington JC"
    "Plant Physiol (2005) 138:2145-2154

  4. PubMed ID: 16954541
    MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent RNA polymerase-2 mutant
    "Lu C, Kulkarni K, Souret FF, MuthuValliappan R, Tej SS, Poethig RS, Henderson IR, Jacobsen SE, Wang W, Green PJ, Meyers BC"
    "Genome Res (2006) 16:1276-1288

  5. PubMed ID: 17182867
    A diverse and evolutionarily fluid set of microRNAs in Arabidopsis thaliana
    "Rajagopalan R, Vaucheret H, Trejo J, Bartel DP"
    "Genes Dev (2006) 20:3407-3425

  6. PubMed ID: 19815687
    Hypoxia-responsive microRNAs and trans-acting small interfering RNAs in Arabidopsis
    "Moldovan D, Spriggs A, Yang J, Pogson BJ, Dennis ES, Wilson IW"
    "J Exp Bot (2010) 61:165-177

  7. PubMed ID: 12226481
    Short RNAs can identify new candidate transposable element families in Arabidopsis
    "Mette MF, van der Winden J, Matzke M, Matzke AJ"
    "Plant Physiol (2002) 130:6-9