Stem-loop mmu-mir-186

Accession

MI0000228

Symbol

MGI: Mir186

Description

Mus musculus mmu-mir-186 precursor miRNA mir-186

Gene
family

RF00697; mir-186

Literature search

34 open access papers mention mmu-mir-186
(222 sentences)

Sequence

238209 reads, 591 reads per million, 107 experiments

acuuucCAAAGAAUUCUCCUUUUGGGCUuucucauuuuauuuuaaGCCCUAAGGUGAAUUUUUUGGGaagu
((((((((((((((((.((((..((((((..............)))))).)))).))))))))))))))))

Structure

                U    UU      ucucau 
acuuucCAAAGAAUUC CCUU  GGGCUu      u
|||||||||||||||| ||||  ||||||       
ugaaGGGUUUUUUAAG GGAA  CCCGaa      u
                U    -U      uuuuau 

Annotation confidence Medium

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context

chr3: 157544279-157544349 [+]

Mature mmu-miR-186-5p

• Accession: MIMAT0000215
• Description: Mus musculus mmu-miR-186-5p mature miRNA
• Sequence: 7 - CAAAGAAUUCUCCUUUUGGGCU - 28
• Evidence: experimental ; cloned [1-3], Illumina [4-5]

Mature mmu-miR-186-3p

• Accession: MIMAT0004540
• Description: Mus musculus mmu-miR-186-3p mature miRNA
• Sequence: 46 - GCCCUAAGGUGAAUUUUUUGGG - 67
• Evidence: experimental ; cloned [3], Illumina [4-5]

References

1. PubMed ID: 12554860
   Numerous microRNPs in neuronal cells containing novel microRNAs
   "Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G"
   "RNA (2003) 9:180-186


2. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


3. PubMed ID: 12554859
   New microRNAs from mouse and human
   "Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T"
   "RNA (2003) 9:175-179


4. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


5. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009