Stem-loop mmu-mir-195a

Accession

MI0000237

Symbol

MGI: Mir195a

Description

Mus musculus mmu-mir-195a precursor miRNA mir-15

Gene
family

RF00455; mir-15

Literature search

100 open access papers mention mmu-mir-195a
(415 sentences)

Sequence

82573 reads, 728 reads per million, 106 experiments

acacccaacucuccuggcucUAGCAGCACAGAAAUAUUGGCauggggaagugagucugCCAAUAUUGGCUGUGCUGCUCCaggcagggugguga
.((((..((((((((((....((((((((((.((((((((((.((.........))))))))))))..))))))))))))))).))))))))).

Structure

a    ca     -     cucU          -A          u  gga 
 cacc  acucu ccugg    AGCAGCACAG  AAUAUUGGCa gg   a
 ||||  ||||| |||||    ||||||||||  |||||||||| ||   g
 gugg  uggga ggaCC    UCGUCGUGUC  UUAUAACCgu cu   u
a    --     c     ----          GG          -  gag 

Annotation confidence High

Genome context

chr11: 70235042-70235135 [+]

Clustered miRNAs

2 other miRNAs are < 10 kb from mmu-mir-195a

Mature mmu-miR-195a-5p

• Accession: MIMAT0000225
• Description: Mus musculus mmu-miR-195a-5p mature miRNA
• Sequence: 21 - UAGCAGCACAGAAAUAUUGGC - 41
• Evidence: experimental ; cloned [1-3], Illumina [4,6]

Mature mmu-miR-195a-3p

• Accession: MIMAT0017000
• Description: Mus musculus mmu-miR-195a-3p mature miRNA
• Sequence: 59 - CCAAUAUUGGCUGUGCUGCUCC - 80
• Evidence: experimental ; 454 [5], Illumina [6]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12554859
   New microRNAs from mouse and human
   "Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T"
   "RNA (2003) 9:175-179


3. PubMed ID: 15538371
   A pancreatic islet-specific microRNA regulates insulin secretion
   "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
   "Nature (2004) 432:226-230


4. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


5. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


6. PubMed ID: 20668074
   Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68
   "Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H"
   "J Virol (2010) 84:10266-10275