Accession
MI0000300
Symbol
HGNC:
MIR223
Description
Homo sapiens
hsa-mir-223 precursor miRNA mir-223
Gene
family?
family?
RF00664;
mir-223
Literature search
400 open access papers mention hsa-mir-223
(2690 sentences)
(2690 sentences)
Sequence
106277
reads,
969
reads per million, 97 experiments
ccuggccuccugcagugccacgcucCGUGUAUUUGACAAGCUGAGUUggacacuccaugugguagagUGUCAGUUUGUCAAAUACCCCAagugcggcacaugcuuaccag
.((((......((((((((.((((..(.((((((((((((((......(((((((.........))))))))))))))))))))).)..)))).))))).)))...))))
.((((......((((((((.((((..(.((((((((((((((......(((((((.........))))))))))))))))))))).)..)))).))))).)))...))))
Structure
c ccuccu - a cC U GAGUUg cau cugg gca gugcc cgcu G GUAUUUGACAAGCU gacacuc g |||| ||| ||||| |||| | |||||||||||||| ||||||| u gacc cgu cacgg guga C CAUAAACUGUUUGA CUGUgag g - ---auu a c AC C ------ aug
Annotation confidence
High
Do you think this miRNA is real?
Comments
This human miRNA was predicted by computational methods using conservation with mouse and Fugu rubripes sequences [1]. Expression of the excised miR has been validated in zebrafish, and the 5' end mapped by PCR. Landgraf et al. confirm expression in human [2]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].
Genome context
chrX: 66018870-66018979 [+]
Disease association
hsa-mir-223 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-223-5p
| Accession | MIMAT0004570 |
| Description | Homo sapiens hsa-miR-223-5p mature miRNA |
| Sequence | 26 - CGUGUAUUUGACAAGCUGAGUU - 47 |
| Evidence |
experimental
cloned [2] |
| Database links |
|
| Predicted targets |
|
Mature hsa-miR-223-3p
| Accession | MIMAT0000280 |
| Description | Homo sapiens hsa-miR-223-3p mature miRNA |
| Sequence | 68 - UGUCAGUUUGUCAAAUACCCCA - 89 |
| Evidence |
experimental
cloned [2] |
| Database links |
|
| Predicted targets |
|
References
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