Stem-loop cel-mir-229

Accession

MI0000304

Description

Caenorhabditis elegans cel-mir-229 precursor miRNA

Literature search

3 open access papers mention cel-mir-229
(11 sentences)

Sequence

104332 reads, 2227 reads per million, 16 experiments

cgccggcAAUGACACUGGUUAUCUUUUCCAUCGuggaaugccccccauugauuuuuuccccuuuucggggggaaaaaauuggaaacgAGAAAGGUAUCGGGUGUCAUAGccggcg
(((((((.((((((((.(.((((((((...((((((......))(((...(((((((((((((...))))))))))))))))..)))))))))))).).)))))))).)))))))

Structure

       A        G U        CCA    ggaaugcccc   uug             u 
cgccggc AUGACACU G UAUCUUUU   UCGu          cca   auuuuuuccccuu  
||||||| |||||||| | ||||||||   ||||          |||   ||||||||||||| u
gcggccG UACUGUGG C AUGGAAAG   Agca          ggu   uaaaaaagggggg  
       A        G U        ---    --------aa   ---             c 

Annotation confidence Medium

Comments

The extents of the dominant mature miRNA species are adjusted here in accordance with a large scale cloning and sequencing study [3].

Genome context

chrIII: 2172452-2172566 [+]

Clustered miRNAs

3 other miRNAs are < 10 kb from cel-mir-229

Mature cel-miR-229-5p

• Accession: MIMAT0000284
• Description: Caenorhabditis elegans cel-miR-229-5p mature miRNA
• Sequence: 8 - AAUGACACUGGUUAUCUUUUCCAUCG - 33
• Evidence: experimental ; cloned [1-2], Northern [1], 454 [3], Illumina [4], CLIPseq [5]

Mature cel-miR-229-3p

• Accession: MIMAT0015112
• Description: Caenorhabditis elegans cel-miR-229-3p mature miRNA
• Sequence: 88 - AGAAAGGUAUCGGGUGUCAUAG - 109
• Evidence: experimental ; CLIPseq [5]

References

1. PubMed ID: 12672692
   The microRNAs of Caenorhabditis elegans
   "Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP"
   "Genes Dev (2003) 17:991-1008


2. PubMed ID: 12747828
   MicroRNAs and other tiny endogenous RNAs in C. elegans
   "Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D"
   "Curr Biol (2003) 13:807-818


3. PubMed ID: 17174894
   Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
   "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
   "Cell (2006) 127:1193-1207


4. PubMed ID: 19460142
   Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
   Kato M, de Lencastre A, Pincus Z, Slack FJ
   Genome Biol (2009) 10:R54


5. PubMed ID: 20062054
   Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
   "Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW"
   "Nat Struct Mol Biol (2010) 17:173-179