Stem-loop mmu-mir-291a

Accession

MI0000389

Symbol

MGI: Mir291a

Description

Mus musculus mmu-mir-291a precursor miRNA mir-290

Gene
family

RF00665; mir-290

Literature search

24 open access papers mention mmu-mir-291a
(93 sentences)

Sequence

57833 reads, 697 reads per million, 46 experiments

ccuauguagcggcCAUCAAAGUGGAGGCCCUCUCUugagccugaaugagAAAGUGCUUCCACUUUGUGUGCcacugcauggg
(((((((((.(((((.((((((((((((.((.(((((........))))).)).)))))))))))))).))).)))))))))

Structure

         c   -  U            C  C     agc 
ccuauguag ggc CA CAAAGUGGAGGC CU UCUug   c
||||||||| ||| || |||||||||||| || |||||    
ggguacguc cCG GU GUUUCACCUUCG GA Agagu   u
         a   U  -            U  A     aag 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr7: 3218919-3219000 [+]

Clustered miRNAs

8 other miRNAs are < 10 kb from mmu-mir-291a

Mature mmu-miR-291a-5p

• Accession: MIMAT0000367
• Description: Mus musculus mmu-miR-291a-5p mature miRNA
• Sequence: 14 - CAUCAAAGUGGAGGCCCUCUCU - 35
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

Mature mmu-miR-291a-3p

• Accession: MIMAT0000368
• Description: Mus musculus mmu-miR-291a-3p mature miRNA
• Sequence: 50 - AAAGUGCUUCCACUUUGUGUGC - 71
• Evidence: experimental ; cloned [1-2], Northern [1], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12919684
   Embryonic stem cell-specific MicroRNAs
   "Houbaviy HB, Murray MF, Sharp PA"
   "Dev Cell (2003) 5:351-358


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009