miRBase entry: mmu-mir-297a-2

Stem-loop mmu-mir-297a-2


Accession
MI0000397
Symbol
MGI: Mir297a-2
Description
Mus musculus mmu-mir-297a-2 precursor miRNA mir-297
Gene
family?
RF04217; mir-297

Literature search
12 open access papers mention mmu-mir-297a-2
(15 sentences)

Sequence

5500 reads, 161 reads per million, 85 experiments
cuguguguauAUGUAUGUGUGCAUGUGCAUGUguguauaugaguauacauauacauacgcacauacccauacaagcaugcacacaaaccc
.(((((((..((((.((((((.((((((..(((((((((((......)))))))))))))))))...)))))).))))))))))).....

Structure
----c       au    A      --C      AU           ag 
     ugugugu  AUGU UGUGUG   AUGUGC  GUguguauaug  u
     |||||||  |||| ||||||   ||||||  |||||||||||   
     acacacg  uacg acauac   uacacg  cauacauauac  a
cccaa       --    a      cca      --           au 


Annotation confidence Not enough data
Do you think this miRNA is real?
Comments
Houbaviy et al. report that the cloned sequence of miR-297 is found over 20 times in the mouse genomic sequence [1]. This sequence appears to match several low complexity repetitive regions. Confidence in which loci actually express miR-297 is low because of the low complexity nature of the sequence.

Genome context
chr2: 10472254-10472343 [+]
Clustered miRNAs
26 other miRNAs are < 10 kb from mmu-mir-297a-2
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-297a-5p

Accession MIMAT0000375
Description Mus musculus mmu-miR-297a-5p mature miRNA
Sequence 11 - AUGUAUGUGUGCAUGUGCAUGU - 32
Evidence experimental
cloned [1], Illumina [2-3]
Database links
Predicted targets

References

  1. PubMed ID: 12919684
    Embryonic stem cell-specific MicroRNAs
    "Houbaviy HB, Murray MF, Sharp PA"
    "Dev Cell (2003) 5:351-358