Stem-loop mmu-mir-297a-2

Accession

MI0000397

Symbol

MGI: Mir297a-2

Description

Mus musculus mmu-mir-297a-2 precursor miRNA mir-297

Gene
family

RF04217; mir-297

Literature search

13 open access papers mention mmu-mir-297a-2
(16 sentences)

Sequence

6774 reads, 59.0 reads per million, 111 experiments

guauAUGUAUGUGUGCAUGUGCAUGUguguauaugaguauacAUAUACAUACGCACAUACCCAUacaag
((((..(((((((((.((((..((((((((((....)))))))))))))).)))))))))..))))...

Structure

---    AU         C    GC          a 
   guau  GUAUGUGUG AUGU  AUGUguguau u
   ||||  ||||||||| ||||  ||||||||||  
   caUA  CAUACACGC UACA  UAUAcauaug g
gaa    CC         A    --          a 

Annotation confidence High

Comments

Houbaviy et al. report that the cloned sequence of miR-297 is found over 20 times in the mouse genomic sequence [1]. This sequence appears to match several low complexity repetitive regions. Confidence in which loci actually express miR-297 is low because of the low complexity nature of the sequence.

Genome context

2: 10477071-10477139 [+]

Clustered miRNAs

19 other miRNAs are < 10 kb from mmu-mir-297a-2

Mature mmu-miR-297a-5p

• Accession: MIMAT0000375
• Description: Mus musculus mmu-miR-297a-5p mature miRNA
• Sequence: 5 - AUGUAUGUGUGCAUGUGCAUGU - 26
• Evidence: experimental ; cloned [1], Illumina [2-3]

Mature mmu-miR-297a-2-3p

• Accession: MIMAT0050678
• Description: Mus musculus mmu-miR-297a-2-3p mature miRNA
• Sequence: 43 - AUAUACAUACGCACAUACCCAU - 64
• Evidence: experimental ; cloned [1], Illumina [2-3]

References

1. PubMed ID: 12919684
   Embryonic stem cell-specific MicroRNAs
   "Houbaviy HB, Murray MF, Sharp PA"
   "Dev Cell (2003) 5:351-358