Stem-loop mmu-mir-298

Accession

MI0000398

Symbol

MGI: Mir298

Description

Mus musculus mmu-mir-298 precursor miRNA

Literature search

27 open access papers mention mmu-mir-298
(136 sentences)

Sequence

350557 reads, 866 reads per million, 102 experiments

ccaggccuuuGGCAGAGGAGGGCUGUUCUUCCCuugaguuuuaugacuggGAGGAACUAGCCUUCUCUCAGCUUaggagugg
(((..(((..(((.(((((((((((((((((((...((((....))))))))))))).))))))).))).))).)))..)))

Structure

   gg   uu   A   -       -         uug    u 
cca  ccu  GGC GAG GAGGGCU GUUCUUCCC   aguu u
|||  |||  ||| ||| ||||||| |||||||||   ||||  
ggu  gga  UCG CUC CUUCCGA CAAGGAGgg   ucag a
   ga   -U   A   U       U         ---    u 

Annotation confidence Medium

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr2: 174267504-174267585 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from mmu-mir-298

Mature mmu-miR-298-5p

• Accession: MIMAT0000376
• Description: Mus musculus mmu-miR-298-5p mature miRNA
• Sequence: 11 - GGCAGAGGAGGGCUGUUCUUCCC - 33
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

Mature mmu-miR-298-3p

• Accession: MIMAT0017007
• Description: Mus musculus mmu-miR-298-3p mature miRNA
• Sequence: 51 - GAGGAACUAGCCUUCUCUCAGCUU - 74
• Evidence: experimental ; Illumina [4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12919684
   Embryonic stem cell-specific MicroRNAs
   "Houbaviy HB, Murray MF, Sharp PA"
   "Dev Cell (2003) 5:351-358


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009