Stem-loop hsa-mir-138-2

Accession

MI0000455

Symbol

HGNC: MIR138-2

Description

Homo sapiens hsa-mir-138-2 precursor miRNA mir-138

Gene
family

RF00671; mir-138

Literature search

226 open access papers mention hsa-mir-138-2
(1607 sentences)

Sequence

73255 reads, 512 reads per million, 82 experiments

cguugcugcAGCUGGUGUUGUGAAUCAGGCCGacgagcagcgcauccucuuacccgGCUAUUUCACGACACCAGGGUUgcauca
.(.(((.((..(((((((((((((...(((((..(((.((......)))))...)))))..))))))))))))).)).))).).

Structure

c u   u  AG             UCA     -ac   c  cg 
 g ugc gc  CUGGUGUUGUGAA   GGCCG   gag ag  c
 | ||| ||  |||||||||||||   |||||   ||| ||   
 c acg UG  GACCACAGCACUU   UCGgc   uuc uc  a
a u   U  -G             -UA     cca   -  cu 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr16: 56858518-56858601 [+]

Disease association

hsa-mir-138-2 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-138-5p

• Accession: MIMAT0000430
• Description: Homo sapiens hsa-miR-138-5p mature miRNA
• Sequence: 10 - AGCUGGUGUUGUGAAUCAGGCCG - 32
• Evidence: experimental ; cloned [2]

Mature hsa-miR-138-2-3p

• Accession: MIMAT0004596
• Description: Homo sapiens hsa-miR-138-2-3p mature miRNA
• Sequence: 57 - GCUAUUUCACGACACCAGGGUU - 78
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 17616659
   Patterns of known and novel small RNAs in human cervical cancer
   "Lui WO, Pourmand N, Patterson BK, Fire A"
   "Cancer Res (2007) 67:6031-6043


3. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739