Stem-loop hsa-mir-193a

Accession

MI0000487

Symbol

HGNC: MIR193A

Description

Homo sapiens hsa-mir-193a precursor miRNA mir-193

Gene
family

RF01895; mir-193

Literature search

148 open access papers mention hsa-mir-193a
(1073 sentences)

Sequence

88886 reads, 387 reads per million, 159 experiments

cgaggaugggagcugagggcUGGGUCUUUGCGGGCGAGAUGAgggugucggaucAACUGGCCUACAAAGUCCCAGUucucggcccccg
.......(((.(((((((((((((.(((((.((((.((.(((..........))).)).)))).))))).))))))))))))).))).

Structure

cgaggau   a             U     C    G  A   gggu 
       ggg gcugagggcUGGG CUUUG GGGC AG UGA    g
       ||| ||||||||||||| ||||| |||| || |||     
       ccc cggcucuUGACCC GAAAC UCCG UC Acu    u
------g   c             U     A    G  A   aggc 

Annotation confidence High

Comments

This miRNA sequence is predicted based on homology to a verified miRNA from mouse [1], later verified in human [2].

Genome context

chr17: 31559996-31560083 [+]

Disease association

hsa-mir-193a is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-193a-5p

• Accession: MIMAT0004614
• Description: Homo sapiens hsa-miR-193a-5p mature miRNA
• Sequence: 21 - UGGGUCUUUGCGGGCGAGAUGA - 42
• Evidence: experimental ; cloned [2-3]

Mature hsa-miR-193a-3p

• Accession: MIMAT0000459
• Description: Homo sapiens hsa-miR-193a-3p mature miRNA
• Sequence: 55 - AACUGGCCUACAAAGUCCCAGU - 76
• Evidence: experimental ; cloned [2-3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 17616659
   Patterns of known and novel small RNAs in human cervical cancer
   "Lui WO, Pourmand N, Patterson BK, Fire A"
   "Cancer Res (2007) 67:6031-6043


3. PubMed ID: 12554859
   New microRNAs from mouse and human
   "Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T"
   "RNA (2003) 9:175-179