Stem-loop hsa-mir-195

Accession

MI0000489

Symbol

HGNC: MIR195

Description

Homo sapiens hsa-mir-195 precursor miRNA mir-15

Gene
family

RF00455; mir-15

Literature search

231 open access papers mention hsa-mir-195
(1860 sentences)

Sequence

191769 reads, 755 reads per million, 153 experiments

agcuucccuggcucUAGCAGCACAGAAAUAUUGGCacagggaagcgagucugCCAAUAUUGGCUGUGCUGCUCCaggcaggguggug
.(((.(((((.((..((((((((((.((((((((((..((........))))))))))))..))))))))))..)).))))).))).

Structure

a   u     g  cU          -A          ca  gaa 
 gcu cccug cu  AGCAGCACAG  AAUAUUGGCa  gg   g
 ||| ||||| ||  ||||||||||  ||||||||||  ||    
 ugg gggac ga  UCGUCGUGUC  UUAUAACCgu  cu   c
g   u     g  CC          GG          --  gag 

Annotation confidence High

Comments

This miRNA sequence is predicted based on homology to a verified miRNA from mouse [1], later verified in human [2].

Genome context

chr17: 7017615-7017701 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-195

Disease association

hsa-mir-195 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-195-5p

• Accession: MIMAT0000461
• Description: Homo sapiens hsa-miR-195-5p mature miRNA
• Sequence: 15 - UAGCAGCACAGAAAUAUUGGC - 35
• Evidence: experimental ; cloned [2]

Mature hsa-miR-195-3p

• Accession: MIMAT0004615
• Description: Homo sapiens hsa-miR-195-3p mature miRNA
• Sequence: 53 - CCAAUAUUGGCUGUGCUGCUCC - 74
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12554859
   New microRNAs from mouse and human
   "Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T"
   "RNA (2003) 9:175-179