Stem-loop mmu-mir-30c-2

Accession

MI0000548

Symbol

MGI: Mir30c-2

Description

Mus musculus mmu-mir-30c-2 precursor miRNA

Literature search

212 open access papers mention mmu-mir-30c-2
(1301 sentences)

Sequence

512704 reads, 1547 reads per million, 107 experiments

gagugacagauauUGUAAACAUCCUACACUCUCAGCugugaaaaguaagaaagCUGGGAGAAGGCUGUUUACUCUcucugccuu
(((.(.((((....(((((((.(((...(((((((((..............))))))))).))).)))))))....))))))))

Structure

   u a    uauU       U   ACA         gugaaa 
gag g caga    GUAAACA CCU   CUCUCAGCu      a
||| | ||||    ||||||| |||   |||||||||       
uuc c gucu    CAUUUGU GGA   GAGGGUCga      g
   - -    cUCU       C   --A         aagaau 

Annotation confidence High

Comments

miR-30c was cloned and mapped to chromosome 4 in reference [1] (MIR:MI0000547). A search of more recent mouse genome assemblies suggests the presence of a second locus encoding miR-30c on chromosome 1, represented by this entry.

Genome context

chr1: 23291701-23291784 [+]

Mature mmu-miR-30c-5p

• Accession: MIMAT0000514
• Description: Mus musculus mmu-miR-30c-5p mature miRNA
• Sequence: 14 - UGUAAACAUCCUACACUCUCAGC - 36
• Evidence: experimental ; cloned [1-4], Illumina [5-6]

Mature mmu-miR-30c-2-3p

• Accession: MIMAT0005438
• Description: Mus musculus mmu-miR-30c-2-3p mature miRNA
• Sequence: 54 - CUGGGAGAAGGCUGUUUACUCU - 75
• Evidence: experimental ; cloned [4], Illumina [5-6]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739


3. PubMed ID: 15538371
   A pancreatic islet-specific microRNA regulates insulin secretion
   "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
   "Nature (2004) 432:226-230


4. PubMed ID: 16766679
   Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
   "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
   "Genes Dev (2006) 20:1732-1743


5. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


6. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009