Stem-loop mmu-mir-27a

Accession

MI0000578

Symbol

MGI: Mir27a

Description

Mus musculus mmu-mir-27a precursor miRNA mir-27

Gene
family

RF00644; mir-27

Literature search

164 open access papers mention mmu-mir-27a
(1508 sentences)

Sequence

628514 reads, 4193 reads per million, 107 experiments

uggccugaggagcAGGGCUUAGCUGCUUGUGAGCAagguccacagcaaagucgugUUCACAGUGGCUAAGUUCCGCccccuggaccc
.((((.(.((.((.(((((((((((((.(((((((.((............)).)))))))))))))))))))).)).))).)).)).

Structure

u  -  u a  a  A             U       a  uccac 
 gg cc g gg gc GGGCUUAGCUGCU GUGAGCA gg     a
 || || | || || ||||||||||||| ||||||| ||      
 cc gg c cc CG CUUGAAUCGGUGA CACUUgu cu     g
c  a  u -  c  C             -       g  gaaac 

Annotation confidence Medium

Genome context

chr8: 84208672-84208758 [+]

Clustered miRNAs

3 other miRNAs are < 10 kb from mmu-mir-27a

Mature mmu-miR-27a-5p

• Accession: MIMAT0004633
• Description: Mus musculus mmu-miR-27a-5p mature miRNA
• Sequence: 14 - AGGGCUUAGCUGCUUGUGAGCA - 35
• Evidence: experimental ; cloned [5], Illumina [6-7]

Mature mmu-miR-27a-3p

• Accession: MIMAT0000537
• Description: Mus musculus mmu-miR-27a-3p mature miRNA
• Sequence: 56 - UUCACAGUGGCUAAGUUCCGC - 76
• Evidence: experimental ; cloned [1-2,4-5], Northern [1], Illumina [6]

References

1. PubMed ID: 12554860
   Numerous microRNPs in neuronal cells containing novel microRNAs
   "Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G"
   "RNA (2003) 9:180-186


2. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


3. PubMed ID: 12919684
   Embryonic stem cell-specific MicroRNAs
   "Houbaviy HB, Murray MF, Sharp PA"
   "Dev Cell (2003) 5:351-358


4. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739


5. PubMed ID: 15538371
   A pancreatic islet-specific microRNA regulates insulin secretion
   "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
   "Nature (2004) 432:226-230


6. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


7. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009