Stem-loop mmu-mir-33

Accession

MI0000707

Symbol

MGI: Mir33

Description

Mus musculus mmu-mir-33 precursor miRNA

Literature search

61 open access papers mention mmu-mir-33
(813 sentences)

Sequence

46129 reads, 316 reads per million, 105 experiments

cugugGUGCAUUGUAGUUGCAUUGCAuguucuggcaauaccugugCAAUGUUUCCACAGUGCAUCACgg
((((((((((((((.(..((((((((((....((.....))))))))))))..).))))))))))))))

Structure

              A UU          uucu  c 
cugugGUGCAUUGU G  GCAUUGCAug    gg a
|||||||||||||| |  ||||||||||    || a
ggCACUACGUGACA C  UGUAACgugu    cc u
              C UU          ----  a 

Annotation confidence High

Comments

Mouse mir-33 is predicted [2] based on homology to a cloned miR from human (MIR:MI0000091) [1]. Its expression was later verified by cloning [3].

Genome context

chr15: 82198122-82198190 [+]

Mature mmu-miR-33-5p

• Accession: MIMAT0000667
• Description: Mus musculus mmu-miR-33-5p mature miRNA
• Sequence: 6 - GUGCAUUGUAGUUGCAUUGCA - 26
• Evidence: experimental ; cloned [3], Illumina [4-5]

Mature mmu-miR-33-3p

• Accession: MIMAT0004666
• Description: Mus musculus mmu-miR-33-3p mature miRNA
• Sequence: 46 - CAAUGUUUCCACAGUGCAUCAC - 67
• Evidence: experimental ; cloned [3], Illumina [4-5]

References

1. PubMed ID: 11679670
   Identification of novel genes coding for small expressed RNAs
   "Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T"
   "Science (2001) 294:853-858


2. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


5. PubMed ID: 15634332
   New human and mouse microRNA genes found by homology search
   "Weber MJ"
   "FEBS J (2005) 272:59-73