miRBase entry: mmu-mir-365-1

Stem-loop mmu-mir-365-1


Accession
MI0000768
Symbol
MGI: Mir365-1
Description
Mus musculus mmu-mir-365-1 precursor miRNA mir-365
Gene
family?
RF00659; mir-365

Literature search
25 open access papers mention mmu-mir-365-1
(93 sentences)

Sequence

19968 reads, 353 reads per million, 105 experiments
accgcagggaaaaugAGGGACUUUUGGGGGCAGAUGUGuuuccauuccgcuaucaUAAUGCCCCUAAAAAUCCUUAUugcucuugca
...((((((..((((((((..(((((((((((..((((...............)))).))))))))))).))))))))..)))))).

Structure
acc      aa        AC           GA    uuucca 
   gcaggg  aaugAGGG  UUUUGGGGGCA  UGUG      u
   ||||||  ||||||||  |||||||||||  ||||      u
   cguucu  uUAUUCCU  AAAAUCCCCGU  AUac      c
--a      cg        -A           -A    uaucgc 


Annotation confidence High
Do you think this miRNA is real?
Comments
Xie et al. [1] refer to this sequence by the internal identifier MIR245. The sequence is unrelated to C. elegans mir-245 (MIR:MI0000321).

Genome context
chr16: 13453840-13453926 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from mmu-mir-365-1
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-365-1-5p

Accession MIMAT0017077
Description Mus musculus mmu-miR-365-1-5p mature miRNA
Sequence 16 - AGGGACUUUUGGGGGCAGAUGUG - 38
Evidence experimental
Illumina [4]
Database links
Predicted targets

Mature mmu-miR-365-3p

Accession MIMAT0000711
Description Mus musculus mmu-miR-365-3p mature miRNA
Sequence 56 - UAAUGCCCCUAAAAAUCCUUAU - 77
Evidence experimental
cloned [2], Illumina [3-4]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  3. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009

  4. PubMed ID: 15735639
    Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals
    "Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M"
    "Nature (2005) 434:338-345