Stem-loop hsa-mir-370

Accession

MI0000778

Symbol

HGNC: MIR370

Description

Homo sapiens hsa-mir-370 precursor miRNA mir-370

Gene
family

RF00740; mir-370

Literature search

76 open access papers mention hsa-mir-370
(823 sentences)

Sequence

12486 reads, 16 reads per million, 96 experiments

agacagagaagcCAGGUCACGUCUCUGCAGUUACacagcucacgaguGCCUGCUGGGGUGGAACCUGGUcugucu
((((((....(((((((..((((((.((((...(((.........))).)))).))))))..)))))))))))))

Structure

      agaa       CA      U    UUA   agc 
agacag    gcCAGGU  CGUCUC GCAG   Cac   u
||||||    |||||||  |||||| ||||   |||   c
ucuguc    UGGUCCA  GUGGGG CGUC   Gug   a
      ----       AG      U    --C   agc 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context

chr14: 100911139-100911213 [+]

Disease association

hsa-mir-370 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-370-3p

• Accession: MIMAT0000722
• Description: Homo sapiens hsa-miR-370-3p mature miRNA
• Sequence: 48 - GCCUGCUGGGGUGGAACCUGGU - 69
• Evidence: experimental ; cloned [1-3], Illumina [4]

Mature hsa-miR-370-5p

• Accession: MIMAT0026483
• Description: Homo sapiens hsa-miR-370-5p mature miRNA
• Sequence: 13 - CAGGUCACGUCUCUGCAGUUAC - 34
• Evidence: experimental ; Illumina [4]

References

1. PubMed ID: 15183728
   Human embryonic stem cells express a unique set of microRNAs
   "Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS, Moon SY, Kim VN, Kim KS"
   "Dev Biol (2004) 270:488-498


2. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


3. PubMed ID: 16274478
   Identification of clustered microRNAs using an ab initio prediction method
   Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
   BMC Bioinformatics (2005) 6:267


4. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45