Stem-loop hsa-mir-375

Accession

MI0000783

Symbol

HGNC: MIR375

Description

Homo sapiens hsa-mir-375 precursor miRNA mir-375

Gene
family

RF00700; mir-375

Literature search

256 open access papers mention hsa-mir-375
(1718 sentences)

Sequence

258382 reads, 632 reads per million, 138 experiments

ccccGCGACGAGCCCCUCGCACAAACCggaccugagcguUUUGUUCGUUCGGCUCGCGUGAggc
.((((((.((((((...((.(((((.((........)).))))).))...)))))))))).)).

Structure

c  -    A      CCU  C     C  gac 
 cc cGCG CGAGCC   CG ACAAA Cg   c
 || |||| ||||||   || ||||| ||    
 gg GUGC GCUCGG   GC UGUUU gc   u
c  A    -      CUU  U     u  gag 

Annotation confidence High

Genome context

chr2: 219001645-219001708 [-]

Disease association

hsa-mir-375 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-375-3p

• Accession: MIMAT0000728
• Description: Homo sapiens hsa-miR-375-3p mature miRNA
• Sequence: 40 - UUUGUUCGUUCGGCUCGCGUGA - 61
• Evidence: experimental ; cloned [2]

Mature hsa-miR-375-5p

• Accession: MIMAT0037313
• Description: Homo sapiens hsa-miR-375-5p mature miRNA
• Sequence: 5 - GCGACGAGCCCCUCGCACAAACC - 27
• Evidence: not_experimental

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15538371
   A pancreatic islet-specific microRNA regulates insulin secretion
   "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
   "Nature (2004) 432:226-230