Stem-loop hsa-mir-377

Accession

MI0000785

Symbol

HGNC: MIR377

Description

Homo sapiens hsa-mir-377 precursor miRNA

Literature search

65 open access papers mention hsa-mir-377
(519 sentences)

Sequence

2013 reads, 24 reads per million, 87 experiments

uugagcAGAGGUUGCCCUUGGUGAAUUCgcuuuauuuauguugaAUCACACAAAGGCAACUUUUGUuug
..((((((((((((((.(((((((.(((((.........).)))))))).))).)))))))))))))).

Structure

uu              C   -    A    - uuu 
  gagcAGAGGUUGCC UUG GUGA UUCg c   a
  |||||||||||||| ||| |||| |||| |   u
  uuUGUUUUCAACGG AAC CACU Aagu g   u
-g              A   A    -    u uau 

Annotation confidence High

Genome context

chr14: 101062050-101062118 [+]

Clustered miRNAs

14 other miRNAs are < 10 kb from hsa-mir-377

Disease association

hsa-mir-377 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-377-5p

• Accession: MIMAT0004689
• Description: Homo sapiens hsa-miR-377-5p mature miRNA
• Sequence: 7 - AGAGGUUGCCCUUGGUGAAUUC - 28
• Evidence: experimental ; cloned [3]

Mature hsa-miR-377-3p

• Accession: MIMAT0000730
• Description: Homo sapiens hsa-miR-377-3p mature miRNA
• Sequence: 45 - AUCACACAAAGGCAACUUUUGU - 66
• Evidence: experimental ; cloned [1-3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15891114
   Clustering and conservation patterns of human microRNAs
   "Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H"
   "Nucleic Acids Res (2005) 33:2697-2706


3. PubMed ID: 16274478
   Identification of clustered microRNAs using an ab initio prediction method
   Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
   BMC Bioinformatics (2005) 6:267