Stem-loop hsa-mir-133b

Accession

MI0000822

Symbol

HGNC: MIR133B

Description

Homo sapiens hsa-mir-133b precursor miRNA

Literature search

328 open access papers mention hsa-mir-133b
(1862 sentences)

Sequence

12384 reads, 266 reads per million, 108 experiments

ccucagaagaaagaugcccccugcucuggcuggucaaacggaaccaaguccgucuuccugagaggUUUGGUCCCCUUCAACCAGCUAcagcagggcuggcaaugcccaguccuuggaga
..............(((((((((((.((((((((..((.((.((((((.((.((((...)))))))))))).)).))..)))))))).)))))))..))))....(((.....)))...

Structure

----ccucagaagaaaga    --       c        ca  c  a      u  g    c 
                  ugcc  cccugcu uggcuggu  aa gg accaag cc ucuu  
                  ||||  ||||||| ||||||||  || || |||||| || |||| c
                  acgg  gggacga AUCGACCA  UU CC UGGUUU gg agag  
agagguuccugacccgua    uc       c        AC  C  C      -  -    u 

Annotation confidence Not enough data

Comments

miR-133b was predicted based on comparative analysis of human, mouse and Fugu [1], and later verified in human [2].

Genome context

chr6: 52148923-52149041 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-133b

Disease association

hsa-mir-133b is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-133b

• Accession: MIMAT0000770
• Description: Homo sapiens hsa-miR-133b mature miRNA
• Sequence: 66 - UUUGGUCCCCUUCAACCAGCUA - 87
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12624257
   Vertebrate microRNA genes
   "Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP"
   "Science (2003) 299:1540