miRBase entry: rno-let-7a-1

Stem-loop rno-let-7a-1

Rattus norvegicus rno-let-7a-1 precursor miRNA
Gene family
MIPF0000002; let-7

Literature search
113 open access papers mention rno-let-7a-1
(866 sentences)


3838625 reads, 3545 reads per million, 513 experiments

u     g     U                     uuagg   aca    c 
 ucacu uggga GAGGUAGUAGGUUGUAUAGUU     guc   ccca c
 ||||| ||||| |||||||||||||||||||||     |||   ||||  
 agugg auCCU UUCUGUCAUCUAACAUAUCaa     uag   gggu a
u     a     -                     -----   --a    c 

Annotation confidence High
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Genome context
chr17: 16417853-16417946 [+]
Clustered miRNAs
4 other miRNAs are < 10 kb from rno-let-7a-1
Name Accession Chromosome Start End Strand Confidence

Database links

Mature rno-let-7a-5p

Accession MIMAT0000774
Description Rattus norvegicus rno-let-7a-5p mature miRNA
Evidence experimental
cloned [1-4], SOLiD [5]

Mature rno-let-7a-1-3p

Accession MIMAT0017085
Description Rattus norvegicus rno-let-7a-1-3p mature miRNA
Evidence experimental
SOLiD [5]


  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 16766679
    Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
    "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
    "Genes Dev (2006) 20:1732-1743

  3. PubMed ID: 14691248
    Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
    "Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G"
    "Proc Natl Acad Sci U S A (2004) 101:360-365

  4. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249

  5. PubMed ID: 15345052
    Microarray analysis of microRNA expression in the developing mammalian brain
    Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
    Genome Biol (2004) 5:R68