Stem-loop rno-mir-34a

Accession

MI0000877

Description

Rattus norvegicus rno-mir-34a precursor miRNA

Literature search

130 open access papers mention rno-mir-34a
(1805 sentences)

Sequence

133513 reads, 189 reads per million, 486 experiments

ccggcugugaguaauucuuUGGCAGUGUCUUAGCUGGUUGUugugaguauuagcuaaggaagcAAUCAGCAAGUAUACUGCCCUAgaagugcugcacguugu
.((((.(((((((.((((..(((((((((((.((((((((((...(((....))).....))))))))))))).))))))))..)))).)))).))))))).

Structure

c    u   -    a    uU        -   A          --gug   a 
 cggc gug agua uucu  GGCAGUGU CUU GCUGGUUGUu     agu u
 |||| ||| |||| ||||  |||||||| ||| ||||||||||     |||  
 guug cac ucgu aagA  CCGUCAUA GAA CGACUAAcga     ucg u
u    -   g    g    UC        U   -          aggaa   a 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context

chr5: 167092491-167092592 [+]

Mature rno-miR-34a-5p

• Accession: MIMAT0000815
• Description: Rattus norvegicus rno-miR-34a-5p mature miRNA
• Sequence: 20 - UGGCAGUGUCUUAGCUGGUUGU - 41
• Evidence: experimental ; cloned [1-2], SOLiD [3]

Mature rno-miR-34a-3p

• Accession: MIMAT0017106
• Description: Rattus norvegicus rno-miR-34a-3p mature miRNA
• Sequence: 64 - AAUCAGCAAGUAUACUGCCCUA - 85
• Evidence: experimental ; SOLiD [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 14691248
   Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
   "Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G"
   "Proc Natl Acad Sci U S A (2004) 101:360-365


3. PubMed ID: 20403161
   Small RNA expression and strain specificity in the rat
   Linsen SE, de Wit E, de Bruijn E, Cuppen E
   BMC Genomics (2010) 11:249