Stem-loop rno-mir-128-1

Accession

MI0000900

Description

Rattus norvegicus rno-mir-128-1 precursor miRNA

Literature search

17 open access papers mention rno-mir-128-1
(63 sentences)

Sequence

3608357 reads, 2708 reads per million, 494 experiments

ugagcuguuggauuCGGGGCCGUAGCACUGUCUGAgagguuuacauuucUCACAGUGAACCGGUCUCUUUuucagcugcuuc
.((((.((((((...(((((((...((((((..(((((((....)))))))))))))...)))))))...)))))).)))).

Structure

u    u      uuC       UAG      CU       u 
 gagc guugga   GGGGCCG   CACUGU  GAgaggu u
 |||| ||||||   |||||||   ||||||  |||||||  
 uucg cgacuu   CUCUGGC   GUGACA  CUcuuua a
c    u      UUU       CAA      --       c 

Annotation confidence High

Comments

The most commonly cloned mature sequences derived from the previously annotated mir-128a and mir-128b were shown by Landgraf et al to be identical [3]. The sequences are therefore renamed mir-128-1 and mir-128-2.

Genome context

chr13: 44916534-44916615 [+]

Mature rno-miR-128-1-5p

• Accession: MIMAT0017118
• Description: Rattus norvegicus rno-miR-128-1-5p mature miRNA
• Sequence: 15 - CGGGGCCGUAGCACUGUCUGA - 35
• Evidence: experimental ; SOLiD [3]

Mature rno-miR-128-3p

• Accession: MIMAT0000834
• Description: Rattus norvegicus rno-miR-128-3p mature miRNA
• Sequence: 50 - UCACAGUGAACCGGUCUCUUU - 70
• Evidence: experimental ; cloned [1-4], Northern [1], SOLiD [5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20403161
   Small RNA expression and strain specificity in the rat
   Linsen SE, de Wit E, de Bruijn E, Cuppen E
   BMC Genomics (2010) 11:249


3. PubMed ID: 15345052
   Microarray analysis of microRNA expression in the developing mammalian brain
   Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
   Genome Biol (2004) 5:R68