Stem-loop rno-mir-186

Accession

MI0000931

Description

Rattus norvegicus rno-mir-186 precursor miRNA

Literature search

64 open access papers mention rno-mir-186
(201 sentences)

Sequence

2291043 reads, 2722.0 reads per million, 517 experiments

ugcuuacaacuuucCAAAGAAUUCUCCUUUUGGGCUUUcucauuuuauuuuaaGCCCAAAGGUGAAUUUUUUGGGaaguuugagcu
.(((((.(((((((((((((((((.(((((.((((((..............))))))))))).)))))))))))))))))))))).

Structure

u     c                 U     U      Ucucau 
 gcuua aacuuucCAAAGAAUUC CCUUU GGGCUU      u
 ||||| ||||||||||||||||| ||||| ||||||       
 cgagu uugaaGGGUUUUUUAAG GGAAA CCCGaa      u
u     -                 U     -      uuuuau 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context

chr2: 263873759-263873844 [+]

Mature rno-miR-186-5p

• Accession: MIMAT0000863
• Description: Rattus norvegicus rno-miR-186-5p mature miRNA
• Sequence: 15 - CAAAGAAUUCUCCUUUUGGGCUUU - 38
• Evidence: experimental ; cloned [1-3], SOLiD [4]

Mature rno-miR-186-3p

• Accession: MIMAT0017143
• Description: Rattus norvegicus rno-miR-186-3p mature miRNA
• Sequence: 54 - GCCCAAAGGUGAAUUUUUUGGG - 75
• Evidence: experimental ; SOLiD [4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16766679
   Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
   "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
   "Genes Dev (2006) 20:1732-1743


3. PubMed ID: 20403161
   Small RNA expression and strain specificity in the rat
   Linsen SE, de Wit E, de Bruijn E, Cuppen E
   BMC Genomics (2010) 11:249


4. PubMed ID: 17805466
   Cloning and identification of novel microRNAs from rat hippocampus
   "He X, Zhang Q, Liu Y, Pan X"
   "Acta Biochim Biophys Sin (Shanghai) (2007) 39:708-714