Stem-loop ebv-mir-BHRF1-1

Accession

MI0001064

Description

Epstein Barr virus ebv-mir-BHRF1-1 precursor miRNA

Sequence

uauUAACCUGAUCAGCCCCGGAGUUgccuguuucaucacuaaccccgggccugaagagguugacaa
..(((((((..((((.(((((.((((..((......)).)))).))))).))))..)))))))...

Structure

-ua       GA    C     A    cc  uu 
   uUAACCU  UCAG CCCGG GUUg  ug  u
   |||||||  |||| ||||| ||||  ||   
   aguugga  aguc gggcc caau  ac  c
aac       ga    c     c    -c  ua 

Annotation confidence Not enough data

Comments

Pfeffer et al. cloned 5 miRNAs from a Burkitt's lymphoma cell line (BL41) infected with the B95-8 strain of Epstein-Barr virus [1]. They were all confirmed by Northern blot.

Genome context

HHV507799: 41471-41536 [+]

Clustered miRNAs

2 other miRNAs are < 10 kb from ebv-mir-BHRF1-1

Disease association

ebv-mir-BHRF1-1 is associated with one or more human diseases in the Human microRNA Disease Database

Mature ebv-miR-BHRF1-1

• Accession: MIMAT0000995
• Description: Epstein Barr virus ebv-miR-BHRF1-1 mature miRNA
• Sequence: 4 - UAACCUGAUCAGCCCCGGAGUU - 25
• Evidence: experimental ; cloned [1-2], Northern [1]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15118162
   Identification of virus-encoded microRNAs
   "Pfeffer S, Zavolan M, Grasser FA, Chien M, Russo JJ, Ju J, John B, Enright AJ, Marks D, Sander C, Tuschl T"
   "Science (2004) 304:734-736