miRBase entry: dre-mir-10b-1

Stem-loop dre-mir-10b-1


Accession
MI0001364
Description
Danio rerio dre-mir-10b-1 precursor miRNA

Literature search
16 open access papers mention dre-mir-10b-1
(194 sentences)

Sequence

379020 reads, 23943 reads per million, 11 experiments
gucuauauaUACCCUGUAGAACCGAAUUUGUGugaaaaaauaacauucACAGAUUCGAUUCUAGGGGAGUauaugguc
..((((((((.((((.(((((.((((((((((...............)))))))))).))))))))).))))))))..

Structure
gu        A    G     C          ugaaaa 
  cuauauaU CCCU UAGAA CGAAUUUGUG      a
  |||||||| |||| ||||| ||||||||||      a
  gguauaUG GGGG AUCUU GCUUAGACAc      u
cu        A    -     A          uuacaa 


Annotation confidence High
Do you think this miRNA is real?
Comments
The miR-10b sequence described in [1] is offset by 2 nt with respect to that cloned in mouse (MIR:MI0000221).

Genome context
chr9: 1952956-1953033 [-]

Database links

Mature dre-miR-10b-5p

Accession MIMAT0001268
Description Danio rerio dre-miR-10b-5p mature miRNA
Sequence 10 - UACCCUGUAGAACCGAAUUUGUG - 32
Evidence experimental
cloned [1]
Database links
Predicted targets

Mature dre-miR-10b-3p

Accession MIMAT0031919
Description Danio rerio dre-miR-10b-3p mature miRNA
Sequence 49 - ACAGAUUCGAUUCUAGGGGAGU - 70
Evidence not_experimental
Database links

References

  1. PubMed ID: 12624257
    Vertebrate microRNA genes
    "Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP"
    "Science (2003) 299:1540

  2. PubMed ID: 15937218
    The developmental miRNA profiles of zebrafish as determined by small RNA cloning
    "Chen PY, Manninga H, Slanchev K, Chien M, Russo JJ, Ju J, Sheridan R, John B, Marks DS, Gaidatzis D, Sander C, Zavolan M, Tuschl T"
    "Genes Dev (2005) 19:1288-1293

  3. PubMed ID: 16736008
    The zebrafish hoxDb cluster has been reduced to a single microRNA
    "Woltering JM, Durston AJ"
    "Nat Genet (2006) 38:601-602