Stem-loop mmu-mir-448

Accession

MI0001638

Symbol

MGI: Mir448

Description

Mus musculus mmu-mir-448 precursor miRNA mir-448

Gene
family

RF00723; mir-448

Literature search

8 open access papers mention mmu-mir-448
(17 sentences)

Sequence

2052 reads, 50 reads per million, 24 experiments

acgaggagguuGAACAUCCUGCAUAGUGCUGCCaggaaaucccuacuucauacuaagagggggcuggcuggUUGCAUAUGUAGGAUGUCCCAUcuccuggcccacuucguca
.(.(((((((.(.((((((((((((.(((.(((((....(((((.(((......)))))))).....))))).))))))))))))))).).))))))).)............

Structure

-----------a g       u A            G   U     -gaaa     a   ca 
            c aggaggu G ACAUCCUGCAUA UGC GCCag     ucccu cuu  u
            | ||||||| | |||||||||||| ||| |||||     ||||| |||   
            g uccucUA C UGUAGGAUGUAU ACG Ugguc     gggga gaa  a
acugcuucaccc g       C C            -   U     ggucg     -   uc 

Annotation confidence High

Comments

Xie et al. [1] refer to this sequence by the internal identifier MIR64. The sequence is unrelated to C. elegans mir-64 (MIR:MI0000035).

Genome context

chrX: 147158210-147158321 [+]

Mature mmu-miR-448-5p

• Accession: MIMAT0017176
• Description: Mus musculus mmu-miR-448-5p mature miRNA
• Sequence: 12 - GAACAUCCUGCAUAGUGCUGCC - 33
• Evidence: experimental ; Illumina [3]

Mature mmu-miR-448-3p

• Accession: MIMAT0001533
• Description: Mus musculus mmu-miR-448-3p mature miRNA
• Sequence: 72 - UUGCAUAUGUAGGAUGUCCCAU - 93
• Evidence: experimental ; Illumina [2-3]

References

1. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


2. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


3. PubMed ID: 15735639
   Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals
   "Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M"
   "Nature (2005) 434:338-345