Stem-loop mmu-mir-365-2

Accession

MI0001645

Symbol

MGI: Mir365-2

Description

Mus musculus mmu-mir-365-2 precursor miRNA mir-365

Gene
family

RF00659; mir-365

Literature search

24 open access papers mention mmu-mir-365-2
(92 sentences)

Sequence

28142 reads, 264 reads per million, 105 experiments

agagugaucaaggacagcaagaaaaaugAGGGACUUUCAGGGGCAGCUGUGuuuccugacucagucaUAAUGCCCCUAAAAAUCCUUAUuguucuugcagugugcaucggag
....((((...(.((.(((((((.((((((((..(((.(((((((((((.(((....))).)))).....))))))).))).)))))))).))))))).)).)..))))...

Structure

agag    caa g  a       a        AC   C       -----    U   u 
    ugau   g ac gcaagaa aaugAGGG  UUU AGGGGCA     GCUG Guu c
    ||||   | || ||||||| ||||||||  ||| |||||||     |||| |||  
    gcua   u ug cguucuu uUAUUCCU  AAA UCCCCGU     ugac cag c
-gag    -cg g  a       g        -A   A       AAUac    u   u 

Annotation confidence High

Comments

Xie et al. [1] refer to this sequence by the internal identifier MIR190. The sequence is unrelated to mammalian mir-190 (MIR:MI0000486).

Genome context

chr11: 79726400-79726511 [+]

Mature mmu-miR-365-3p

• Accession: MIMAT0000711
• Description: Mus musculus mmu-miR-365-3p mature miRNA
• Sequence: 68 - UAAUGCCCCUAAAAAUCCUUAU - 89
• Evidence: experimental ; cloned [2], Illumina [3-4]

Mature mmu-miR-365-2-5p

• Accession: MIMAT0017179
• Description: Mus musculus mmu-miR-365-2-5p mature miRNA
• Sequence: 29 - AGGGACUUUCAGGGGCAGCUGUG - 51
• Evidence: experimental ; Illumina [4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


3. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


4. PubMed ID: 15735639
   Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals
   "Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M"
   "Nature (2005) 434:338-345