miRBase entry: hcmv-mir-US5-2

Stem-loop hcmv-mir-US5-2

Accession

MI0001683

Description

Human cytomegalovirus hcmv-mir-US5-2 precursor miRNA

Sequence

ggaggCUUUCGCCACACCUAUCCUGAAAGcguugcauucuuUAUGAUAGGUGUGACGAUGUCUuu
.(((((..(((.((((((((((..(((.((...)).))).....)))))))))).))).))))).

Structure

g     UU   C          ---CU   A  g 
 gaggC  UCG CACACCUAUC     GAA Gc  
 |||||  ||| ||||||||||     ||| || u
 uUCUG  AGC GUGUGGAUAG     cuu cg  
u     -U   A          UAUuu   a  u

Annotation confidence Not enough data

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Genome context

HEHCMVCG: 196189-196253 [+]

Clustered miRNAs

2 other miRNAs are < 10 kb from hcmv-mir-US5-2

Name	Accession	Chromosome	Start	End	Strand	Confidence

Disease association

hcmv-mir-US5-2 is associated with one or more human diseases in the Human microRNA Disease Database

Disease	Description	Category	PubMed ID

Database links

Mature hcmv-miR-US5-2-3p

Accession	MIMAT0001580
Description	Human cytomegalovirus hcmv-miR-US5-2-3p mature miRNA
Sequence	42 - UAUGAUAGGUGUGACGAUGUCU - 63
Evidence	experimental cloned [1-2], Illumina [3]

Mature hcmv-miR-US5-2-5p

Accession	MIMAT0026553
Description	Human cytomegalovirus hcmv-miR-US5-2-5p mature miRNA
Sequence	6 - CUUUCGCCACACCUAUCCUGAAAG - 29
Evidence	experimental Illumina [3]

References

PubMed ID: 17604727
A mammalian microRNA expression atlas based on small RNA library sequencing
"Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
"Cell (2007) 129:1401-1414

PubMed ID: 15782219
Identification of microRNAs of the herpesvirus family
"Pfeffer S, Sewer A, Lagos-Quintana M, Sheridan R, Sander C, Grasser FA, van Dyk LF, Ho CK, Shuman S, Chien M, Russo JJ, Ju J, Randall G, Lindenbach BD, Rice CM, Simon V, Ho DD, Zavolan M, Tuschl T"
"Nat Methods (2005) 2:269-276

PubMed ID: 22013051
High-resolution profiling and analysis of viral and host small RNAs during human cytomegalovirus infection
"Stark TJ, Arnold JD, Spector DH, Yeo GW"
"J Virol (2012) 86:226-235