Stem-loop dre-let-7a-5

Accession

MI0001862

Description

Danio rerio dre-let-7a-5 precursor miRNA

Literature search

43 open access papers mention dre-let-7a-5
(316 sentences)

Sequence

56430590 reads, 55502.0 reads per million, 305 experiments

guacguguuuuuggugucuggacaaggUGAGGUAGUAGGUUGUAUAGUUUggugggagggaucaaacccuguucagcugauaaCUAUACAGUCUAUUGCCUUCCUUgugucaccuaaggucugc
............((((...(.((((((.(((((((((((((((((((((.(.((((((((......)))).)))).)....))))))))))))))))))))))))))).)))))..........

Structure

guacguguuuuu    ucu g      U                     ---U g    -    au 
            ggug   g acaagg GAGGUAGUAGGUUGUAUAGUU    g uggg aggg  c
            ||||   | |||||| |||||||||||||||||||||    | |||| ||||   
            ccac   u ugUUCC UUCCGUUAUCUGACAUAUCaa    c acuu uccc  a
--cgucuggaau    --- g      -                     uagu g    g    aa 

Annotation confidence High

Genome context

chr23: 5431196-5431319 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from dre-let-7a-5

Mature dre-let-7a-5p

• Accession: MIMAT0001759
• Description: Danio rerio dre-let-7a-5p mature miRNA
• Sequence: 28 - UGAGGUAGUAGGUUGUAUAGUUU - 50
• Evidence: experimental ; cloned [1]

Mature dre-let-7a-5-3p

• Accession: MIMAT0060862
• Description: Danio rerio dre-let-7a-5-3p mature miRNA
• Sequence: 84 - CUAUACAGUCUAUUGCCUUCCUU - 106
• Evidence: experimental ; cloned [1]

References

1. PubMed ID: 15937218
   The developmental miRNA profiles of zebrafish as determined by small RNA cloning
   "Chen PY, Manninga H, Slanchev K, Chien M, Russo JJ, Ju J, Sheridan R, John B, Marks DS, Gaidatzis D, Sander C, Zavolan M, Tuschl T"
   "Genes Dev (2005) 19:1288-1293